Agent Name |
Phenyl ether, vapor |
Alternative Name |
Diphenyl ether |
CAS Number |
101-84-8 |
Formula |
C12-H10-O |
Major Category |
Other Classes |
Synonyms |
1,1'-Oxybis(benzene); Benzene, 1,1'-oxybis-; Benzene, phenoxy-; Biphenyl oxide; Chemcryl JK-EB; Diphenyl ether; Diphenyl oxide; Ether, diphenyl-; Geranium crystals; Oxybisbenzene; Oxydiphenyl; Phenoxybenzene; Phenyl oxide; [ChemIDplus] UN3077 |
Category |
Other Aromatics |
Description |
Colorless, crystalline solid or liquid (above 82 degrees F) with a geranium-like odor; [NIOSH] |
Sources/Uses |
Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants; [ACGIH] |
Comments |
Damage to the liver and other organs has been documented in acute studies of experimental animals; [ACGIH] An irritant of the eyes and respiratory tract; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
1 ppm |
STEL (ACGIH) |
2 ppm |
PEL (OSHA) |
1 ppm |
MAK |
1 ppm |
IDLH (NIOSH) |
100 ppm |
Excerpts from Documentation for IDLHs |
Other animal data: Rats exposed to 20 ppm for 7 hours per day for 20 days exhibited only eye and nasal irritation [Hefner et al. 1975]. Human data: It has been reported that industrial experience has shown no evidence that phenyl ether, either as a liquid, mist, or vapor, is a health hazard under ordinary conditions of production and use; no overt systemic toxicity was found at concentrations that were not intolerably disagreeable [Clayton and Clayton 1981]. |
Vapor Pressure |
0.02 mm Hg |
Odor Threshold Low |
0.1 ppm |
Explanatory Notes |
Odor threshold (recognition) from CHEMINFO; Flash point = 115 deg C; |
Flammability (NFPA) |
1: must be preheated |
Adverse Effects |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIPHENYL ETHER
|
|
|