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Agent Name Phenyl ether, vapor
Alternative Name Diphenyl ether
CAS Number 101-84-8
Formula C12-H10-O
Major Category Other Classes
Synonyms 1,1'-Oxybis(benzene); Benzene, 1,1'-oxybis-; Benzene, phenoxy-; Biphenyl oxide; Chemcryl JK-EB; Diphenyl ether; Diphenyl oxide; Ether, diphenyl-; Geranium crystals; Oxybisbenzene; Oxydiphenyl; Phenoxybenzene; Phenyl oxide; [ChemIDplus] UN3077
Category Other Aromatics
Description Colorless, crystalline solid or liquid (above 82 degrees F) with a geranium-like odor; [NIOSH]
Sources/Uses Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants; [ACGIH]
Comments Damage to the liver and other organs has been documented in acute studies of experimental animals; [ACGIH] An irritant of the eyes and respiratory tract; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 1 ppm
STEL (ACGIH) 2 ppm
PEL (OSHA) 1 ppm
MAK 1 ppm
IDLH (NIOSH) 100 ppm
Excerpts from Documentation for IDLHs Other animal data: Rats exposed to 20 ppm for 7 hours per day for 20 days exhibited only eye and nasal irritation [Hefner et al. 1975]. Human data: It has been reported that industrial experience has shown no evidence that phenyl ether, either as a liquid, mist, or vapor, is a health hazard under ordinary conditions of production and use; no overt systemic toxicity was found at concentrations that were not intolerably disagreeable [Clayton and Clayton 1981].
Vapor Pressure 0.02 mm Hg
Odor Threshold Low 0.1 ppm
Explanatory Notes Odor threshold (recognition) from CHEMINFO; Flash point = 115 deg C;
Flammability (NFPA) 1: must be preheated
Adverse Effects
Hepatotoxin Hepatotoxin, Secondary
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: DIPHENYL ETHER  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Other InformationNo other related information on this agent was found.





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Last updated: January, 2009