| Agent Name |
Pentachloronaphthalene |
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| CAS Number |
1321-64-8 |
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| Formula |
C10-H3-Cl5 |
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| Major Category |
Other Classes |
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| Synonyms |
Halowax 1013; [NIOSH] |
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| Category |
Halowaxes |
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| Description |
Pale-yellow or white solid or powder with an aromatic odor; [NIOSH] |
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| Sources/Uses |
Used as additives to lubricants and cable insulation (fire retardants); [ACGIH] |
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| Comments |
Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. A skin and eye irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| Bioaccumulates |
Yes |
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| TLV (ACGIH) |
0.5 mg/m3 |
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| PEL (OSHA) |
0.5 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: AIHA [1970] reported that the atmospheric concentration immediately hazardous to life is probably unattainable for the chloronaphthalenes with the possible exception of monochloronaphthalene. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for pentachloronaphthalene remains "Unknown." |
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| Vapor Pressure |
1.49 x 10 -05 mm Hg |
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| Adverse Effects |
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| Dermatotoxin |
Chloracne |
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| Hepatotoxin |
Hepatotoxin, Primary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PENTACHLORONAPHTHALENE
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