| Agent Name |
Phenyl glycidyl ether |
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| Alternative Name |
PGE |
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| CAS Number |
122-60-1 |
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| Formula |
C9-H10-O2 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
(+/-)-(2,3-Epoxypropyl)phenylether; (Phenoxymethyl)oxirane; 1,2-Epoxy-3-phenoxypropane; 1-Phenoxy-2,3-epoxypropane; 2,3-Epoxy-1-phenoxypropane; 2,3-Epoxypropyl phenyl ether; 2,3-Epoxypropylphenyl ether; 3-Phenoxy-1,2-epoxypropane; 3-Phenoxy-1,2-propylene oxide; 3-Phenyloxy-1,2-epoxypropane; Ageflex PGE; Benzene, (2,3-epoxypropoxy)-; Ether, 2,3-epoxypropyl phenyl; Ether, phenylglycidyl; Fenyl-glycidylether [Czech]; Glycidol phenyl ether; Glycidyl phenyl ether; Heloxy WC-63; Oxirane, (phenoxymethyl)-; PGE; Phenol glycidyl ether; Phenol-glycidaether [German]; Phenoxypropene oxide; Phenoxypropylene oxide; Phenyl 2,3-epoxypropyl ether; Phenylglycidyl ether; Phenylglycydyl ether; Propane, 1,2-epoxy-3-phenoxy-; [ChemIDplus] UN8027 |
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| Category |
Glycidyl Ethers |
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| Description |
Colorless liquid. [Note: A solid below 38 degrees F.] [NIOSH] |
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| Sources/Uses |
Glycidyl ethers are used as reactive diluents in epoxy resins. [LaDou, p. 508] Allergic contact dermatitis in shoemakers; [Marks] |
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| Comments |
PGE is a testicular toxin in male rats exposed by inhalation at 12 ppm for 19 days. [ACGIH] A skin irritant and sensitizer; [ICSC] Can cause narcosis, reproductive effects, and possible hematopoietic effects; [CAMEO] Animals have CNS depression and evidence of liver injury in high-dose studies. [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
0.1 ppm |
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| PEL (OSHA) |
10 ppm |
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| IDLH (NIOSH) |
100 ppm |
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| Excerpts from Documentation for IDLHs |
ACGIH [1971] reported that 10 rats exposed to 100 ppm phenyl glycidyl ether 7 hours/day for 50 days exhibited no immediately obvious signs of toxicity, and no deaths occurred [Hine et al. 1956]. |
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| Vapor Pressure |
0.01 mm Hg |
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| Lethal Concentration |
LC50 (rats) >100 ppm/8h |
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| Explanatory Notes |
Flash point = 248 deg F; |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PHENYL GLYCIDYL ETHER
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