| Comments |
Sensitization to drugs occurs during production and use:
1. Handling by pharmaceutical chemists and technicians;
2. Packaging and cleaning by manufacturing workers;
3. Hand-compounding by pharmacists;
4. Mixing animal feeds by farmers;
5. Crushing tablets or preparing lyophilized solutions by nurses;
6. Applying topical drugs to patients by nurses or physical therapists; [Kanerva, p. 479]
Allergic Reactions in Pharmacists and Pharmaceutical Workers
OA = Occupational Asthma
ACD = Allergic Contact Dermatitis
CU = Contact Urticaria
PACD = Photoallergic Contact Dermatitis
ANTIBIOTICS
Ampicillin OA CU
Bacitracin ACD CU
Cephalosporins OA CU
Chloramphenicol ACD CU
Gentamycin ACD CU
Iodochlorhydroxyquin (Vioform) ACD CU
Isoniazid OA
Lincomycin ACD
Mezlocillin CU
Neomycin ACD CU
Nitrofurazone (Furacin) ACD
Pencillin OA CU
Spectinomycin ACD
Spiramycin OA
Streptomycin CU
Sulfanilamide PACD
Tetracyclines OA
Thimerosal (Merthiolate) ACD
Virginiamycin ACD CU
CHEMOTHERAPEUTIC AGENTS
Azathioprine (Imuran) ACD
Cisplatin CU
Mitoxantrone OA
ANTIHYPERTENSIVES
Methyldopa OA
Hydralazine OA ACD
Alprenolol ACD
Labetalol ACD
Oxprenolol ACD
Propanolol ACD
NSAIDS
Benzydamine (Difflam) ACD PACD
Piroxicam (Feldene) ACD
OTHER AGENTS
Azoperone ACD
Benzocaine ACD CU
Cimetidine OA
Chlorpromazine PACD CU
Codeine OA ACD
Disulfiram (Antabuse) ACD
Famotidine (Pepcid) ACD
Ipecac OA
Morphine OA ACD
Penicillamine OA
Promethazine PACD CU
Propacemetol ACD
Phenothiazine PACD CU
Procaine hydrochloride ACD
Psyllium OA
Quinidine ACD
Ranitidine ACD
Salbutamol intermediate OA
Tetracaine ACD
from [Marks] and [Malo]"^^^^^^^0^^^^0^1^0^1^1^0^0^0^0^7^0^0^^"Not evaluated
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