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Agent Name Ethyl benzene
CAS Number 100-41-4
Formula C8-H10
Major Category Solvents
Synonyms Ethylbenzene; Ethylbenzol; Phenylethane; Ethylbenzol; [ChemIDplus] UN1175
Category Aromatic Solvents
Description Colorless liquid with an aromatic odor; [NIOSH]
Sources/Uses Used as a solvent and an intermediate in the production of styrene; [ACGIH] Used as a solvent for resins and coatings; [HSDB]
Comments Liquid causes first degree burns on short exposure. [CHRIS] Mild liver toxicity observed in animal inhalation studies; When exposed at 1000 ppm, humans have profuse lacrimation. [ACGIH]
Reference Link ATSDR ToxFAQs - Ethylbenzene
Exposure Assessment
BEI Sum of Mandelic and Phenylglyoxylic acids in urine = 0.7 g/g creatinine; end of shift at end of workweek; screen for Ethyl benzene in end-exhaled air;
Skin Designation (ACGIH) No
TLV (ACGIH) 100 ppm
STEL (ACGIH) 125 ppm
PEL (OSHA) 100 ppm
IDLH (NIOSH) 800 ppm
Excerpts from Documentation for IDLHs Human data: Dizziness was caused in one volunteer after a 5�minute exposure to 2,000 ppm [Yant et al. 1930].
Vapor Pressure 9.6 mm Hg
Odor Threshold Low 0.09 ppm
Odor Threshold High 0.6 ppm
RD50 1430 ppm
Lethal Concentration LCLo (rats) = 4,000 ppm/4H
Explanatory Notes IDLH = 10% LEL (lower explosive limit); Odor threshold from AIHA; Flash point = 12.8 deg C;
Half Life Whole body: biphasic with initial of 3.1 hours and slower phase of 25 hours; [TDR, p. 631]
Reference Link International Chemical Safety Cards (WHO/IPCS/ILO)
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Dermatotoxin Skin Burns
Neurotoxin CNS Solvent Syndrome
Hepatotoxin Hepatotoxin, Secondary
IARC Carcinogen Possible Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: ETHYLBENZENE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009