Agent Name |
Enflurane |
CAS Number |
13838-16-9 |
Formula |
C3-H2-Cl-F5-O |
Major Category |
Other Uses |
Synonyms |
(+-)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; Anesthetic 347; Anesthetic Compound No. 347; C 347; Compound 347; Efrane; Enflurane; Enflurano [INN-Spanish]; Enfluranum [INN-Latin]; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-, (+-)-; Ethrane; Methylflurether; OHIO 347; [ChemIDplus] |
Category |
Waste Anesthetic Gases |
Description |
Clear, colorless liquid with a mild, sweet odor; inhalation anesthetic; [NIOSH] |
Sources/Uses |
Stable inhalation anesthetic; [ChemIDplus] |
Comments |
See "WASTE ANESTHETIC GASES" Enflurane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
Reference Link |
Volatile Substance Abuse |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
75 ppm |
MAK |
20 ppm |
Vapor Pressure |
591 mm Hg |
Lethal Concentration |
LC50 (rats) = 14,000 ppm/3h |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Reproductive Toxin |
Yes |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
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