Agent Name |
N-Isopropylaniline |
CAS Number |
768-52-5 |
Formula |
C9-H13-N |
Major Category |
Nitrogen Compounds |
Synonyms |
N-IPA; Isopropylaniline; N-(1-Methylethyl)benzenamine; N-Phenylisopropylamine; [NIOSH] |
Category |
Amines, Aromatic |
Description |
Clear, yellowish liquid with a sweet, aromatic odor; [NIOSH] |
Sources/Uses |
Used in synthesis of dyes for acrylic fibers and other chemicals; [ACGIH] |
Comments |
Like aniline and N,N-dimethylaniline, N-isopropylaniline can cause methemoglobinemia after skin and inhalation exposure in the workplace. [ACGIH] Can induce methemoglobinemia; May cause skin sensitization after prolonged contact; [ICSC] |
Exposure Assessment |
BEI |
Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH] |
Skin Designation (ACGIH) |
Yes |
TLV (ACGIH) |
2 ppm |
Vapor Pressure |
0.44 mm Hg |
Lethal Concentration |
LC50 (rats) = 1,100 mg/m3/4h |
Explanatory Notes |
Flash point = 87 deg C; |
Adverse Effects |
Methemoglobinemia |
Methemoglobinemia, Primary |
Skin Sensitizer |
Yes |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-ISOPROPYLANILINE
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