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Agent Name N-Isopropylaniline
CAS Number 768-52-5
Formula C9-H13-N
Major Category Nitrogen Compounds
Synonyms N-IPA; Isopropylaniline; N-(1-Methylethyl)benzenamine; N-Phenylisopropylamine; [NIOSH]
Category Amines, Aromatic
Description Clear, yellowish liquid with a sweet, aromatic odor; [NIOSH]
Sources/Uses Used in synthesis of dyes for acrylic fibers and other chemicals; [ACGIH]
Comments Like aniline and N,N-dimethylaniline, N-isopropylaniline can cause methemoglobinemia after skin and inhalation exposure in the workplace. [ACGIH] Can induce methemoglobinemia; May cause skin sensitization after prolonged contact; [ICSC]
Exposure Assessment
BEI Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]
Skin Designation (ACGIH) Yes
TLV (ACGIH) 2 ppm
Vapor Pressure 0.44 mm Hg
Lethal Concentration LC50 (rats) = 1,100 mg/m3/4h
Explanatory Notes Flash point = 87 deg C;
Adverse Effects
Methemoglobinemia Methemoglobinemia, Primary
Skin Sensitizer Yes
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: N-ISOPROPYLANILINE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009