Agent Name |
Isobutyronitrile |
CAS Number |
78-82-0 |
Formula |
C4-H7-N |
Major Category |
Toxic Gases & Vapors |
Synonyms |
1-Cyano-1-methylethane; 2-Cyanopropane; 2-Methylpropane nitrile; 2-ethylpropanenitrile; 2-Methylpropionitrile; Dimethylacetonitrile; Isobutyronitrile; Isopropyl cyanide; Isopropyl nitrile; Isopropylkyanid [Czech]; Isopropylnitrile; Propanenitrile, 2-methyl-; Propanoic acid, 2-methyl-, nitrile; alpha-Methylpropanenitrile; [ChemIDplus] UN2284 |
Category |
Nitriles |
Description |
Colorless liquid with an almond-like odor; Note: Forms cyanide in the body; [NIOSH] |
Sources/Uses |
Used in the synthesis of insecticides and gasoline additives; used as a catalyst in the production of polyethylene; [HSDB] |
Comments |
Isobutyronitrile is hazardous by the oral, skin, or inhalation routes; it causes liver injury in animal feeding studies. Animals inhaling 5500 ppm for one hour have convulsions and die. [HSDB] |
Exposure Assessment |
Skin Designation (ACGIH) |
Not evaluated |
Vapor Pressure |
32.7 mm Hg |
Lethal Concentration |
LCLo (rats) = 1,000 ppm/4h |
Explanatory Notes |
NIOSH REL = 8 ppm; Flash point = 8 deg C; |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Hepatotoxin |
Hepatotoxin, Secondary |
Other Poison |
Chemical Asphyxiant |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-METHYLPROPANENITRILE
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