| Agent Name |
2-Nitrophenol |
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| CAS Number |
88-75-5 |
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| Formula |
C6-H5-N-O3 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
2-Hydroxynitrobenzene; 2-Nitrophenol; Phenol, 2-nitro-; Phenol, o-nitro-; o-Hydroxynitrobenzene; o-Nitrofenol [Czech]; o-Nitrophenol; [ChemIDplus] UN1663 |
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| Category |
Nitros, Aromatic |
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| Description |
Light yellow solid with a peculiar aromatic smell; |
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| Sources/Uses |
Used to produce drugs, fungicides, and dyes; used to darken leather; [ATSDR ToxProfiles] |
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| Comments |
4-Nitrophenol is more toxic than 2-nitrophenol in animals. Rats exposed to 112 mg/m3 for 2 weeks develop methemoglobinemia. No effect after dust exposures of 30 mg/m3 for 3-6 hours/day, 5 days a week for 4 weeks; [ATSDR ToxProfiles] Can be absorbed through intact skin; [HSDB] A mild skin and eye irritant; Can induce methemoglobinemia after ingestion; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.11 mm Hg |
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| Reference Link |
ATSDR - ToxFAQs - Nitrophenols |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-NITROPHENOL
|
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