Agent Name |
o-Nitrotoluene |
Alternative Name |
2-Nitrotoluene |
CAS Number |
88-72-2 |
Formula |
C7-H7-N-O2 |
Major Category |
Nitrogen Compounds |
Synonyms |
1-Methyl-2-nitrobenzene; 2-Methyl-1-nitrobenzene; 2-Methylnitrobenzene; 2-Nitrotoluene; 2-Nitrotoluol; Nitrotoluene, all isomers; ONT; Toluene, o-nitro-; o-Methylnitrobenzene; o-Nitrotoluene; o-Nitrotoluol; ortho-Nitrotoluol; [ChemIDplus] UN1664 |
Category |
Nitros, Aromatic |
Description |
Yellow liquid with a weak, aromatic odor. [Note: A solid below 25 degrees F.]; [NIOSH] |
Sources/Uses |
Used in the production of dyes, pesticides, and rubber chemicals; [ACGIH] |
Comments |
Nitrotoluenes (all isomers) have the potential to induce methemoglobinemia in the same manner as aniline and nitrobenzene. [ACGIH] Irritating to the eyes; Can induce methemoglobinemia; [ICSC] |
Exposure Assessment |
BEI |
Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH] |
Skin Designation (ACGIH) |
Yes |
TLV (ACGIH) |
2 ppm |
PEL (OSHA) |
5 ppm |
IDLH (NIOSH) |
200 ppm |
Excerpts from Documentation for IDLHs |
Basis for revised IDLH: Based on acute oral toxicity data in animals [Back et al. 1972; Vasilerko et al. 1978] and an analogy to nitrobenzene [Linch 1974] which has an IDLH of 200 ppm, the original IDLH for nitrotoluene (200 ppm) is not being revised at this time. |
Vapor Pressure |
0.1 mm Hg |
Odor Threshold Low |
0.05 ppm |
Lethal Concentration |
LC50 (rats) = 790 mg/m3 |
Explanatory Notes |
Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 95 deg C; |
Flammability (NFPA) |
1: must be preheated |
Adverse Effects |
Methemoglobinemia |
Methemoglobinemia, Primary |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-NITROTOLUENE
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