| Agent Name |
N-Nitrosodimethylamine |
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| Alternative Name |
N,N-Dimethylnitrosoamine |
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| CAS Number |
62-75-9 |
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| Formula |
C2-H6-N2-O |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
DMN; DMNA; Dimethylamine, N-nitroso-; Dimethylnitrosamin [German]; Dimethylnitrosamine; Dimethylnitrosoamine; Methanamine, N-methyl-N-nitroso-; N,N-Dimethylnitrosamine; N-Dimethyl-nitrosamine; N-Methyl-N-nitrosomethanamine; N-Nitroaodimethylamine; N-Nitroso-N,N-dimethylamine; N-Nitrosodimethylamine; NDMA; Nitrosamine, dimethyl-; Nitrosodimethylamine; [ChemIDplus] UN2810 |
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| Category |
Nitrosamines |
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| Description |
Yellow, oily liquid with a faint, characteristic odor; [NIOSH] |
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| Sources/Uses |
Used as an intermediate in the production of 1,1-dimethylhydrazine; DMNA contaminates common organic amines and may occur as a byproduct of industrial processes; [ACGIH] |
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| Comments |
A animal carcinogen; At least one death and a number of cases of hepatic injury have been reported in workers handling DMNA. [ACGIH] A skin, eye, and respiratory tract irritant; May cause liver injury and jaundice; [ICSC] |
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| Restricted |
Regulated as a carcinogen: See 29CFR1910.1003 (Code of Federal Regulation). |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| Vapor Pressure |
3 mm Hg |
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| Odor Threshold Low |
0.0079 ppm |
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| Odor Threshold High |
0.01 ppm |
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| Lethal Concentration |
LC50 (rats) = 78 ppm/4h |
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| Explanatory Notes |
Carcinogen--No TLV; Odor threshold from AIHA; Flash point = 142 deg F; |
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| Half Life |
No reports found; [TDR, p. 955] |
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| Reference Link |
ATSDR ToxFAQs - N-nitrosodimethylamine |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Primary |
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| IARC Carcinogen |
Probable Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-NITROSODIMETHYLAMINE
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