| Agent Name |
Nitroblue tetrazolium |
|---|
| CAS Number |
298-83-9 |
|---|
| Formula |
C40-H30-N10-O6.2Cl |
|---|
| Major Category |
Dyes |
|---|
| Synonyms |
NBT; NBT (dye); Nitro BT; Nitro Blue tetrazolium; Nitro Blue tetrazolium chloride; Nitro Blue tetrazolium salt; Nitro tetrazolium BT; Nitroblue tetrazolium salt; Nitrotetrazolium Blue; Nitrotetrazolium Chloride Blue; Tetrazolium Nitro Blue; Tetrazolium nitro BT; p-Nitro Blue tetrazolium; p-Nitro Blue tetrazolium chloride; p-Nitrotetrazolium Blue; 2H-Tetrazolium, 2,2'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(3-(4-nitrophenyl)-5-phenyl-, chloride (1:2); 2H-Tetrazolium, 3,3'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2-(4-nitrophenyl)-5-phenyl-, dichloride; 5,5'-Diphenyl-3,3'-bis(4-nitrophenyl)-2,2'-(3,3'-dimethoxybiphenyl-4,4'-ylene)ditetrazolium dichloride; [ChemIDplus] |
|---|
| Category |
Other Dyes |
|---|
| Description |
Solid; Color varies (colorless, yellow, blue or black); [ChemIDplus] |
|---|
| Sources/Uses |
"Formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease." [ChemIDplus] A microscopic stain used to detect dehydrogenases and alkaline phosphatase; [Ullmann] |
|---|
| Comments |
May be harmful after ingestion, inhalation, or skin contact; A skin, eye, and respiratory tract irritant; Target organs are liver, heart, kidneys, and eyes. May cause convulsions; LD50 (mouse) = 2000 mg/kg; [MSDSonline] "Moderately toxic by ingestion." [Hawley] |
|---|
| Exposure Assessment |
|---|
| Flammability (NFPA) |
0: will not burn |
|---|
| Adverse Effects |
|---|
| Neurotoxin |
Other CNS Neurotoxin |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Links to Other NLM Databases |
|---|
|
|
