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Agent Name Ninhydrin CAS Number 485-47-2 Formula C9-H6-O4 Major Category Other Classes Synonyms 1,2,3-Indantrione monohydrate; 1,2,3-Indantrione, 2-hydrate; 2,2-Dihydroxy-1,3-indandione; 2,2-Dihydroxy-1H-indene-1,3(2H)-dione; Ninhydrin; Ninhydrin hydrate; Triketohydrindene hydrate; 1,3-Indandione, 2,2-dihydroxy-; 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-; Indan-1,2,3-trione; [ChemIDplus] Category Other Organic Compounds Description White to light yellow crystals or powder; [CAMEO] Sources/Uses Used as a laboratory reagent to detect amino and carboxyl groups in peptides and proteins; [Pirila P et al. Rhinitis caused by ninhydrin develops into occupational asthma. Eur Respir J. 1997, Aug;10(8):1918-21.] Comments Allergic contact dermatitis and occupational asthma reported in a forensic technician; [Malo] A skin, eye, and respiratory tract irritant; May cause skin sensitization after prolonged contact; [ICSC] Reference Link Rhinitis caused by ninhydrin develops into occupational asthma Exposure Assessment Skin Designation (ACGIH) Not evaluated Vapor Pressure 2.36 x 10 -07 mm Hg Reference Link Allergic contact dermatitis from ninhydrin in a forensic scientist Adverse Effects Asthma Yes Skin Sensitizer Yes Links to Other NLM Databases Toxicity Information Search TOXNET Chemical Information Search ChemIDplus Biomedical References Search PubMed Related Information in Haz-Map Diseases Occupational diseases associated with exposure to this agent: Asthma, occupational Contact dermatitis, allergic

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