| Agent Name |
Cumene |
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| CAS Number |
98-82-8 |
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| Formula |
C9-H12 |
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| Major Category |
Solvents |
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| Synonyms |
(1-Methylethyl)benzene; 2-Fenilpropano [Italian]; 2-Fenyl-propaan [Dutch]; 2-Phenylpropane; Benzene, isopropyl; CUMENE; Cumeen [Dutch]; Cumol; Isopropilbenzene [Italian]; Isopropyl-benzol [German]; Isopropylbenzeen [Dutch]; Isopropylbenzene; Isopropylbenzol; Propane, 2-phenyl; [ChemIDplus] UN1918 |
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| Category |
Aromatic Solvents |
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| Description |
Colorless liquid with a sharp, penetrating, aromatic odor; [NIOSH] |
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| Sources/Uses |
Used in surface coatings and high-octane aviation fuel; [ACGIH] |
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| Comments |
Liver toxicity occurs in rats inhaling 500 ppm daily for 5 months. [ACGIH] Inhalation of high concentrations may cause CNS effects; A skin, eye, and respiratory tract irritant; [ICSC] Fatty liver changes are noted in animals exposed to lethal doses; [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
50 ppm |
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| PEL (OSHA) |
50 ppm |
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| MAK |
50 ppm |
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| IDLH (NIOSH) |
900 ppm |
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| Excerpts from Documentation for IDLHs |
Daily exposures of rats to 500 ppm for 5 months resulted in no significant blood changes, although hyperemia and congestion were noted in the lungs, liver, and kidneys [Clayton and Clayton 1981]. |
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| Vapor Pressure |
4.5 mm Hg |
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| Odor Threshold Low |
0.008 ppm |
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| Odor Threshold High |
0.13 ppm |
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| Lethal Concentration |
LCLo (rats) = 8,000 ppm/4H |
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| Explanatory Notes |
IDLH = 10% LEL (lower explosive limit); Detection odor threshold from AIHA (mean = 0.032 ppm); Flash point = 39 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CUMENE
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