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Agent Name Coumaphos
CAS Number 56-72-4
Formula C14-H16-Cl-O5-P-S
Major Category Pesticides
Synonyms 3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate; 3-Chloro-4-methyl-7-hydroxycoumarin diethyl thiophosphoric acid ester; 3-Chloro-4-methylumbelliferone O-ester with O,O-diethyl phosphorothioate; 3-Chloro-7-diethoxyphosphinothioyloxy-4-methylcoumarin; 3-Chloro-7-hydroxy-4-methyl-coumarin O,O-diethyl phosphorothioate; 3-Chloro-7-hydroxy-4-methyl-coumarin O-ester with O,O-diethyl phosphorothioate; Agridip; Asunthol; Asuntol; Azunthol; Baymix; Baymix 50; CO-Ral; Coumafos; Coumafosum [INN-Latin]; Coumaphos; Coumaphos [ISO]; Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester with O,O-diethyl phosphorothioate; Cumafos [Dutch]; Cumafos [INN-Spanish]; Cumafosum; Diethyl 3-chloro-4-methylumbelliferyl thionophosphate; Diethyl thiophosphoric acid ester of 3-chloro-4-methyl-7-hydroxycoumarin; Diethyl-O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate; Diolice; Meldane; Meldone; Muscatox; Negashunt; Negasunt; O,O-Diaethyl-O-(3-chlor-4-methyl-cumarin-7-yl)-monothiophosphat [German]; O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-benzopyran-7-yl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2h-benzopyran-7-yl); phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-7-coumarinyl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methylcoumarinyl-7) thiophosphate; O,O-Diethyl O-(3-chloro-4-methylumbelliferone) thiophosphate; O,O-Diethyl O-(3-chloro-4-methylumbelliferyl)phosphorothioate; O,O-Diethyl-O-(3-chloor-4-methyl-cumarin-7-yl)monothiofosfaat [Dutch]; O,O-Dietil-O-(3-cloro-4-metil-cumarin-7-il-monotiofosfato); [Italian]; O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl phosphorothioate; O-(3-Chloro-4-methyl-7-coumarinyl) O,O-diethylphosphorothioate; O-3-Chloro-4-methyl-7-coumarinyl O,O-diethyl phosphorothioate; OMS 485; Phosphorothioic acid, O,O-diethyl ester, O-ester with 3-chloro-7-hydroxy-4-methylcoumarin; Phosphorothioic acid, O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester; Resitox; Suntol; Thiophosphate de O,O-diethyle et de O-(3-chloro-4-methyl-7-coumarinyle) [French]; Umbethion; [ChemIDplus]
Category Organophosphates
Description Brownish crystals with a slight odor of sulfur; [CAMEO]
Sources/Uses "Used for the control of a wide variety of livestock insects including cattle grubs, lice, scabies, flies, and ticks; the common ectoparasites of sheep, goats, horse, swine, and poultry as well as for screwworms in all these animals." [CAMEO] Used as an insecticide and ascaricide for direct application to cattle, goats, horses, sheep, and swine;
Reference Link EXTOXNET PIP - COUMAPHOS
Exposure Assessment
BEI Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]
Skin Designation (ACGIH) Yes
TLV (ACGIH) 0.05 mg/m3, inhalable fraction and vapor
Vapor Pressure 9.7 x 10 -08 mm Hg
Lethal Concentration LC50 (rats) = 303 mg/m3
Half Life There was no bioaccumulation in rats. 5% of a dermal dose and 70% of an oral dose were eliminated in 7 days. [EXTOXNET]
Adverse Effects
Other Poison Organophosphate
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: COUMAPHOS  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009