| Agent Name |
4-Chloro-2-toluidine |
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| Alternative Name |
4-Chloro-o-toluidine |
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| CAS Number |
95-69-2 |
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| Formula |
C7-H8-Cl-N |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
2-Amino-5-chlorotoluene; 2-Methyl-4-chloroaniline; 3-Chloro-6-aminotoluene; 4-Chloro-2-methylaniline; 4-Chloro-2-methylbenzeneamine; 4-Chloro-2-toluidine; 4-Chloro-6-methylaniline; 4-Chloro-o-toluidine; 5-Chloro-2-aminotoluene; Amarthol Fast Red TR Base; Asymmetric meta-chloro-ortho-toluidine; Azoene Fast Red TR Base; Azoic Diazo Component 11, base; Benzenamine, 4-chloro-2-methyl-; Brentamine Fast Red TR Base; Daito Red Base TR; Deval Red K; Deval Red TR; Diazo Fast Red TRA; Fast Red 5CT Base; Fast Red Base TR; Fast Red TR; Fast Red TR Base; Fast Red TR11; Fast Red TRO Base; Kako Red TR Base; Kambamine Red TR; Mitsui Red TR Base; Red Base Ciba IX; Red Base IRGA IX; Red Base NTR; Red TR Base; Sanyo Fast Red TR Base; Tulabase Fast Red TR; o-Toluidine, 4-chloro-; p-Chloro-o-toluidine; para-Chloro-ortho-toluidine; [ChemIDplus] |
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| Category |
Amines, Aromatic |
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| Description |
Grayish-white crystalline solid; [IARC] |
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| Sources/Uses |
Used in the past to manufacture azo dyes and chlordimeform; [IARC] |
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| Comments |
4-Chloro-2-toluidine is known to cause methemoglobinemia in humans. Two of three cohort studies showed high relative risks for workers exposed to this chemical in dye and chlordimeform production. [IARC] |
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| Restricted |
No longer in production or use in most countries since the 1980s; [IARC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.04 mm Hg |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4-CHLORO-O-TOLUIDINE
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