| Agent Name |
Sulfuryl fluoride |
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| CAS Number |
2699-79-8 |
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| Formula |
F2-O2-S |
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| Major Category |
Pesticides |
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| Synonyms |
Sulfur difluoride dioxide; Vikane�; [NIOSH] UN2191 |
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| Category |
Fumigants |
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| Description |
Colorless, odorless gas. [insecticide/fumigant] [Note: Shipped as a liquefied compressed gas.] [NIOSH] |
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| Sources/Uses |
Used as a structural fumigant to kill termites; [ACGIH] |
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| Comments |
Concentrations inside fumigated structures are as high as 4000 to 40,000 ppm. Inhalation exposure may cause pulmonary edema. [ACGIH] Because sulfuryl fluoride is heavier than air, workers who re-enter a treated area are at risk for fatal hypoxia. Muscle twitching and seizures have been reported after acute poisoning. [EPA Pesticides, p. 161] Possible frostbite from contact with liquid; [NIOSH] The exact toxic mechanism is not known, but increased fluoride ion concentrations have been found in poisoned victims. Systemic fluorosis may result from sulfuryl fluoride poisoning. Fluoride can cause hypocalcemia and hyperkalemia with secondary arrhythmias and central nervous effects including agitation, tetany, and seizures. [AHLS, p. 266-7] This gas has no warning properties, but cloropicrin is often added. After chronic inhalation studies, animals have evidence of liver injury. [HSDB] |
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| Reference Link |
EXTOXNET PIP - SULFURYL FLUORIDE |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TIH |
Yes |
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| TLV (ACGIH) |
5 ppm |
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| STEL (ACGIH) |
10 ppm |
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| PEL (OSHA) |
5 ppm |
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| IDLH (NIOSH) |
200 ppm |
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| Excerpts from Documentation for IDLHs |
Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966]. |
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| Lethal Concentration |
LC50 (rats) = 991 ppm/4H |
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| Explanatory Notes |
Not combustible; [CHEMINFO] |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: SULFURYL FLUORIDE
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