Department of Health and Human Services logoNational Institutes of Health logoNational Heart, Lung, and Blood Institute
NHLBI BannerSearch
Division of Intramural Research Banner
NHLBI Logo Division of Intramural Research NHLBI Logo
LMB Banner LMB Home    NHLBI Research Home
Skip left side navigation and go to content

Sections

Optical Spectroscopy Section

Structural Biophysics Section

 

Resources

Publications

Image Gallery

 

Contact Us

LMB Staff

 
Skip left side navigation and go to content
Skip left side navigation and go to content

Image

Comparison of the N-terminal tail of the human and yeast Fis1 protein. The yeast Fis1 N-terminal sits in the hydrophobic groove of the protein. The hydrophobic interaction between the N-terminal tail and the groove is complemented by electrostatic interactions at the its perimeter. Truncation of this N-terminal tail abolishes Mdv1 recruitment to the mitochondria membrane, thus inhibiting mitochondria fission. This is illustrated by the diffuse profile of the GFP-Mdv1 confocal in yeast transfected with N-terminal truncated Fis1.

Comparison of the N-terminal tail of the human and yeast Fis1 protein. The yeast Fis1 N-terminal sits in the hydrophobic groove of the protein. The hydrophobic interaction between the N-terminal tail and the groove is complemented by electrostatic interactions at the its perimeter. Truncation of this N-terminal tail abolishes Mdv1 recruitment to the mitochondria membrane, thus inhibiting mitochondria fission. This is illustrated by the diffuse profile of the GFP-Mdv1 confocal in yeast transfected with N-terminal truncated Fis1.

 

 

jump over rollover images to navigation links

NHLBI HOME · SEARCH NHLBI · ACCESSIBILITY INFORMATION · NHLBI SITE INDEX · OTHER SITES · PRIVACY STATEMENT · FOIA · CONTACT NHLBI

Department of Health and Human Services National Institutes of Health National Heart, Lung, and Blood Institute