Colorectal Cancer Prevention (PDQ®)
[ patient ] [ health professional ]
Expert-reviewed information summary about factors that may influence the risk of developing of colorectal cancer and about research aimed at the prevention of this disease.
Clinical Trials to Prevent Colon Cancer
Check for colon cancer prevention trials from NCI's PDQ® Cancer Clinical Trials Registry now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.
Clinical Trials to Prevent Rectal Cancer
Check for rectal cancer prevention trials from NCI's PDQ® Cancer Clinical Trials Registry now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.
Celecoxib Significantly Reduces the Risk of Precancerous Colorectal Polyps
Regular use of the COX-2 inhibitor celecoxib (Celebrex®) significantly reduces the risk of precancerous polyps recurring in the colon or rectum, according to the August 31, 2006, issue of the New England Journal of Medicine.
Calcium and Vitamin D Supplements Offer Modest Bone Improvements, No Benefits for Colorectal Cancer
Calcium and vitamin D supplements in healthy, postmenopausal women provide a modest benefit in preserving bone mass and prevent hip fractures in certain groups, including older women, but do not prevent other types of fractures or colorectal cancer, according to the results of a major clinical trial, part of the Women's Health Initiative (WHI).
News from the Women's Health Initiative: Reducing Total Fat Intake May Have Small Effect on Risk of Breast Cancer, No Effect on Risk of Colorectal Cancer, Heart Disease, or Stroke
Following an eating pattern lower in total fat did not significantly reduce the incidence of breast cancer, heart disease, or stroke, and did not reduce the risk of colorectal cancer in healthy postmenopausal women, according to the latest clinical trial results from the Women's Health Initiative.
NCI-Funded Clinical Trials Show Aspirin Reduces Recurrence of Polyps
Taking daily aspirin for as little as three years was shown to reduce the development of colorectal polyps by 19 percent to 35 percent in people at high risk for colorectal cancer in two randomized, controlled clinical trials published in today's New England Journal of Medicine.
NCI-Sponsored Trials of Cyclooxygenase (COX) Inhibitors for Cancer Prevention and Treatment
Numerous compounds are examined by the National Cancer Institute (NCI) for their potential to prevent or treat cancer. Questions and Answers
Trials Show No Effect of Low-Fat, High-Fiber, and High-Fruit and -Vegetable Diets on the Growth of New Colorectal Polyps in People with a History of Precancerous Polyps
Two studies of nutritional interventions in people at high risk of colorectal cancer yielded no evidence that diet affects the growth of precancerous colorectal polyps (adenomatous polyps or adenomas) in people who have already had a polyp removed.
Questions and Answers
Genetics of Colorectal Cancer (PDQ®)
[ health professional ]
Expert-reviewed information summary about the genetics of colorectal cancer, including information about specific genes and family cancer syndromes. The summary also contains information about screening for colorectal cancer and research aimed at prevention of this disease. Psychosocial issues associated with genetic testing and counseling of individuals who may have hereditary colorectal cancer syndrome are also discussed.
Cancer Family Registries
Two international family registries on breast/ovarian cancer and colon cancer offer concerned individuals the opportunity to participate in research, and investigators opportunities to conduct valuable research.
Cancer Genetics Overview (PDQ®)
[ health professional ]
Expert-reviewed information summary in which the validity and utility of genetic tests are discussed and important genetic terms are defined.
Understanding Gene Testing
Illustrates what genes are, explains how mutations occur and are identified within genes, and discusses the benefits and limitations of gene testing for cancer and other disorders.
Search: Cancer Genetics Services Directory
Directory of professionals who provide services related to cancer genetic risk assessment, counseling, and testing.
Cancer Risk: Understanding the Puzzle
An interactive site about cancer risk and how you can make informed decisions about lowering your risk.
Colorectal Cancer Risk Assessment Tool
An interactive tool to help measure a person's risk of developing colorectal cancer.
Heterocyclic Amines in Cooked Meats
A fact sheet that explains how heterocyclic amines (HCA) are created in meat that is well done, fried, or barbecued, and how consuming these chemicals is associated with certain types of cancer. National Cancer Institute Fact Sheet 3.25
Asbestos Exposure: Questions and Answers
A fact sheet about asbestos, asbestos-related diseases, and who to contact for more information. National Cancer Institute Fact Sheet 3.21