| Agent Name |
Methyl isobutyl carbinol |
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| Alternative Name |
Methyl amyl alcohol |
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| CAS Number |
108-11-2 |
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| Formula |
C6-H14-O |
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| Major Category |
Solvents |
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| Synonyms |
(+-)-4-Methyl-2-pentanol; 1,3-Dimethylbutanol; 2-Methyl-4-pentanol; 2-Pentanol, 4-methyl-; 3-MIC; 4-Methyl-2-amyl alcohol; 4-Methyl-2-pentyl alcohol; 4-Methylpentanol-2; 4-Metilpentan-2-olo [Italian]; 4-Pentanol, 2-methyl-; Alcohol methyl amylique [French]; Alcool methyl amylique [French]; Isobutylmethylcarbinol; Isobutylmethylmethanol; M.I.B.C.; MAOH; MIBC; MIC; Methyl amyl alcohol; Methyl isobutyl carbinol; Methyl-isobutylkarbinol [Czech]; Methylisobutyl carbinol; Methylisobutylcarbinol; Metilamil alcohol [Italian]; dl-Methylisobutylcarbinol; [ChemIDplus] UN2053 |
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| Category |
Alcohols and Polyols |
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| Description |
Colorless liquid with a mild odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent for dyestuffs, oils, gums, resins, waxes, etc.; [ACGIH] Used to make lacquers, solvents, plasticizers, and lubricants; [HSDB] |
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| Comments |
In acute animal studies, high concentrations induce narcosis and anesthesia. [ACGIH] Inhalation of high concentrations can cause CNS depression; A skin, eye, and respiratory tract irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
25 ppm |
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| STEL (ACGIH) |
40 ppm |
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| PEL (OSHA) |
25 ppm |
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| MAK |
20 ppm |
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| IDLH (NIOSH) |
400 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: Eye irritation has occurred after exposures to 50 ppm for 15 minutes [Silverman et al. 1946]. |
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| Vapor Pressure |
5.3 mm Hg |
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| Odor Threshold Low |
0.01 ppm |
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| Odor Threshold High |
1 ppm |
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| Lethal Concentration |
LCLo (rats) = 2,000 ppm/4H |
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| Explanatory Notes |
Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 105 deg F; |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4-METHYL-2-PENTANOL
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