| Agent Name |
Isopropyl ether |
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| Alternative Name |
Diisopropyl ether |
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| CAS Number |
108-20-3 |
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| Formula |
C6-H14-O |
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| Major Category |
Solvents |
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| Synonyms |
2,2'-Oxybis-propane; 2-Isopropoxypropane; Bis(isopropyl) ether; Diisopropyl ether; Diisopropyl oxide; Ether isopropylique [French]; Ether, isopropyl; Izopropylowy eter [Polish]; Propane, 2,2'-oxybis-; [ChemIDplus] UN1159 |
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| Category |
Ethers |
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| Description |
Colorless liquid with a sharp, sweet, ether-like odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent for resins, waxes, oils, dyes, and surface coatings; [ACGIH] |
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| Comments |
The odor is "more irritating and less pleasant than that of ethyl ether." [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
250 ppm |
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| STEL (ACGIH) |
310 ppm |
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| PEL (OSHA) |
500 ppm |
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| MAK |
200 ppm |
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| IDLH (NIOSH) |
1400 ppm |
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| Excerpts from Documentation for IDLHs |
Volunteers exposed to 800 ppm for 5 minutes reported irritation of the eyes and nose [Silverman et al. 1946]. |
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| Vapor Pressure |
149 mm Hg |
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| Odor Threshold Low |
0.01 ppm |
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| Odor Threshold High |
0.05 ppm |
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| Lethal Concentration |
LC50 (rats) = 162,000 mg/m3 |
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| Explanatory Notes |
IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 0.017 ppm); Flash point = -28 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ISOPROPYL ETHER
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