| Agent Name |
Isopropyl acetate |
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| CAS Number |
108-21-4 |
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| Formula |
C5-H10-O2 |
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| Major Category |
Solvents |
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| Synonyms |
1-Methylethyl acetate; 2-Acetoxypropane; 2-Propyl acetate; Acetate d'isopropyle [French]; Acetic Acid, isopropyl ester; Acetic acid, 1-methylethyl ester; Isopropile (acetato di) [Italian]; Isopropyl (acetate d') [French]; Isopropyl acetate; Isopropyl ethanoate; Isopropylacetaat [Dutch]; Isopropylacetat [German]; Isopropyle (acetate d') [French]; Isopropylester kyseliny octove [Czech]; Paracetat; [ChemIDplus] UN1220 |
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| Category |
Esters |
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| Description |
Colorless liquid with a fruity odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent and flavoring agent; [ACGIH] Solvent uses include nitrocellulose, resins, paints, lacquers, inks, insecticides, and perfumes; [Hawley] |
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| Comments |
A skin, eye, and respiratory tract irritant; Inhalation of high concentrations far above the OEL can cause CNS depression; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
100 ppm |
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| STEL (ACGIH) |
200 ppm |
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| PEL (OSHA) |
250 ppm |
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| MAK |
100 ppm |
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| IDLH (NIOSH) |
1800 ppm |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1970] report that a 4�hour exposure to 16,000 ppm killed 1 of 6 rats. . . . Other animal data: It has been stated that isopropyl acetate is comparable in toxicity to ethyl acetate and n�propyl acetate [ACGIH 1991].
Human data: None relevant for use in determining the revised IDLH; |
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| Vapor Pressure |
60.4 mm Hg |
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| Odor Threshold Low |
0.5 ppm |
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| Odor Threshold High |
34 ppm |
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| Lethal Concentration |
LC50 (rats) = 50,600 mg/m3/8H |
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| Explanatory Notes |
IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 4.1 ppm); Flash point = 2 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ISOPROPYL ACETATE
|
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