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Agent Name Isoamyl acetate
Alternative Name 3-Methylbutyl acetate, Isopentyl acetate
CAS Number 123-92-2
Formula C7-H14-O2
Major Category Solvents
Synonyms 1-Butanol, 3-methyl-, acetate; 2-Methylbutyl ethanoate; 3-Methyl-1-butanol acetate; 3-Methyl-1-butyl acetate; 3-Methylbutyl acetate; 3-Methylbutyl ethanoate; Acetic acid, 3-methylbutyl ester; Acetic acid, isopentyl ester; Amyl acetate, common; Amylacetic ester; Banana oil; I-Amyl acetate; Isoamyl acetate; Isoamyl acetate (natural); Isoamyl ethanoate; Isoamylester kyseliny octove [Czech]; Isopentyl acetate; Isopentyl alcohol, acetate; Isopentyl ethanoate; Pear oil; beta-Methylbutyl acetate; [ChemIDplus] UN1993
Category Esters
Description Colorless liquid with a banana-like odor; [NIOSH]
Sources/Uses Used as a solvent and flavoring agent; [ACGIH]
Comments Esters may induce narcosis in animal experiments, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 50 ppm
STEL (ACGIH) 100 ppm
PEL (OSHA) 100 ppm
MAK 50 ppm
IDLH (NIOSH) 1000 ppm
Excerpts from Documentation for IDLHs " Isoamyl acetate is considered more irritating than butyl acetate. Exposure to 1,000 ppm for 30 minutes resulted in irritation, dyspnea, fatigue, and increased pulse [Amor 1950]. It is considered dangerous to life after 5 hours of exposure to 10,000 ppm [Browning 1965]." [NIOSH]
Vapor Pressure 5.6 mm Hg
Odor Threshold Low 0.0034 ppm
Odor Threshold High 209 ppm
Explanatory Notes Detection odor threshold from AIHA (mean = 0.22 ppm); Flash point = 77 deg F;
Half Life No reports found; [TDR, p. 95]
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: ISOAMYL ACETATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009