Agent Name |
n-Butyl acetate |
Alternative Name |
Butyl acetate |
CAS Number |
123-86-4 |
Formula |
C6-H12-O2 |
Major Category |
Solvents |
Synonyms |
1-Butyl acetate; Acetate de butyle [French]; Acetic acid n-butyl ester; Acetic acid, butyl ester; Butile (acetati di) [Italian]; Butyl acetate; Butyl ethanoate; Butylacetat [German]; Butylacetaten [Dutch]; Butyle (acetate de) [French]; Butylester kyseliny octove [Czech]; Octan n-butylu [Polish]; n-Butyl acetate; n-Butyl acetate (natural); n-Butyl ethanoate; [ChemIDplus] UN1123 |
Category |
Esters |
Description |
Colorless liquid with a fruity odor; [NIOSH] |
Sources/Uses |
Used in the manufacture of lacquers and plastics; [ACGIH] |
Comments |
Narcosis induced in acute animal studies; [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
150 ppm |
STEL (ACGIH) |
200 ppm |
PEL (OSHA) |
150 ppm |
MAK |
100 ppm |
IDLH (NIOSH) |
1700 ppm |
Excerpts from Documentation for IDLHs |
Other animal data: A 4�hour exposure to 10,000 ppm was not lethal to rats [Smyth 1956].
Human data: Severe irritation of the throat has been reported in volunteers exposed to 300 ppm for 3 to 5 minutes [Nelson et al. 1943]. However, it has also been reported that irritation of the eyes and nose is first objectionable at 3,300 ppm and that higher concentrations cause tearing and hyperemia of the conjunctiva [Grant 1974] |
Vapor Pressure |
11.5 mm Hg |
Odor Threshold Low |
0.06 ppm |
Odor Threshold High |
7.4 ppm |
Lethal Concentration |
LC50 (rats) = 390 ppm/4H |
Explanatory Notes |
IDLH = 10% LEL (lower explosive limit); Detection odor threshold from AIHA (mean = 0.31 ppm); Flash point = 22 deg C; |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-BUTYL ACETATE
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