| Agent Name |
VM & P Naphtha |
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| CAS Number |
8032-32-4 |
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| Major Category |
Solvents |
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| Synonyms |
Ligroin; Painters naphtha; Petroleum ether; Petroleum spirit; Refined solvent naphtha; Varnish Makers' & painters' naphtha; [NIOSH] UN1993 |
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| Category |
Refined Petroleum |
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| Description |
Clear to yellowish liquid with a pleasant, aromatic odor; There are several different VM & P naphthas based on different petroleum fractions. [ACGIH] |
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| Sources/Uses |
VM & P naphtha has been used as a paint solvent. [ACGIH] |
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| Comments |
Petroleum distillates, e.g., VM & P naphtha and kerosene, can cause anesthesia, slowing of reflexes and dermatitis. They may contain n-hexane with the potential to cause peripheral neuropathy. [LaDou, p. 500-1] With regard to potential liver injury, fatty infiltration may be seen after heavy exposures to petroleum distillates, but "frank necrosis is uncommon." [Haddad, L.M., Clinical Management of Poisoning and Drug Overdose. 2nd ed. Philadelphia, PA: W.B. Saunders Co., 1990.(Reference in HSDB for petroleum distillates)] Petroleum ether is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] |
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| Reference Link |
Volatile Substance Abuse |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
300 ppm |
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| Vapor Pressure |
40 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 3,400 ppm/4h |
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| Explanatory Notes |
See 2008 Notice of Intended Changes; [ACGIH] Flash point = 20 deg F; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: LIGROINE
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