| Agent Name |
1,3-Dioxolane |
|---|
| Alternative Name |
Formal glycol |
|---|
| CAS Number |
646-06-0 |
|---|
| Formula |
C3-H6-O2 |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
1,3-Dioxacyclopentane; 1,3-Dioxolan; 1,3-Dioxole, dihydro-; Dioxolan [Czech]; Dioxolane; Ethylene glycol formal; Formal glycol; Glycol formal; Glycol methylene ether; Glycolformal; [ChemIDplus] |
|---|
| Category |
Ethers |
|---|
| Description |
Colorless liquid with a mild, ethereal odor; [ACGIH] |
|---|
| Sources/Uses |
Used as a solvent and extractant for fats, waxes, and dyes; Used in the production of phenolic-novolak resins; [HSDB] Used as a monomer to produce polyacetals and a solvent for polyesters, vinyls, and epoxys; May be used as a paint stripper; [ACGIH] |
|---|
| Comments |
In animal studies, 1,3-dioxolane is a CNS depressant and has some effects on the liver; [HSDB] A skin irritant and severe eye irritant; Blood (leukopenia) and reproductive changes occur in animal studies. [ACGIH] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
20 ppm |
|---|
| Vapor Pressure |
70 mm Hg |
|---|
| Lethal Concentration |
LC50 (rats) = 20,650 mg/m3/4H |
|---|
| Flammability (NFPA) |
3: may ignite at ambient temperature |
|---|
| Adverse Effects |
|---|
| Neurotoxin |
CNS Solvent Syndrome |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Reproductive Toxin |
Yes |
|---|
| Links to Other NLM Databases |
|---|
|
|
