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| The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS.
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Health Effects
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HARMFUL IF SWALLOWED OR ABSORBED THROUGH SKIN.
DO NOT BREATH VAPOR OR SPRAY MIST. AVOID CONTACT WITH EYES, SKIN OR CLOTHING. KEEP OUT OF REACH OF CHILDREN
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From MSDS
POTENTIAL HEALTH EFFECTS
EYES: This substance is not expected to cause prolonged or significant eye irritation.
SKIN: This substance is not expected to cause skin irritation and is only slightly toxic if absorbed through the skin. See Toxicological Information, section 11.
INGESTION: This substance is slightly toxic to internal organs if swallowed. The degree of injury will depend on the amount absorbed from the gut.
INHALATION: Breathing the vapor may be irritating to the respiratory tract. If inhaled, this substance is considered practically non-toxic to internal organs.
TARGET ORGANS: Diazinon is an inhibitor of the cholinesterase enzyme, found in nervous tissue, red blood cells, and plasma.
SENSITIZATION: This product contains trace quantities of methylisothiazolinone and methylchloroisothiazolinone as preservatives. At higher concentrations these preservatives have been shown to cause allergic skin reactions in susceptible individuals. These preservatives are also found in a number of widely used personal care products, such as shampoos and cosmetics.
COMMENTS HEALTH: Depending upon the extent and degree of overexposure to the product, signs and symptoms of cholinesterase inhibition can result following either ingestion, skin contact or inhalation routes of exposure. Signs and symptoms of cholinesterase inhibition can also result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) exposure to the product.
Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.
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From MSDS
Depending upon the extent and degree of overexposure to the product, signs and symptoms of cholinesterase inhibition can result following either ingestion, skin contact or inhalation routes of exposure. Signs and symptoms of cholinesterase inhibition can also result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) exposure to the product.
Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.
SENSITIZATION: No evidence of allergic skin reactions was observed in guinea pigs following repeated skin exposure.
NEUROTOXICITY: Diazinon is not considered to produce organophosphate induced delayed neuropathy. Results of chicken neurotoxicity studies were negative.
TERATOGENICITY: Diazinon is not considered to be a teratogen (a substance that causes birth defects). The rat and rabbit developmental NOEL's (no observable effect level) were 20 and 100 mg/kg/dy, respectively.
REPRODUCTIVE TOXIN: Diazinon is not considered to be a reproductive toxin. Results of a rat multigeneration reproduction study indicated that the daily dietary NOEL (No Observable Effect Level) for diazinon was 0.5 mg/kg/dy. The maternal maximum tolerated dose was 25 mg/kg/dy.
MUTAGENICITY: Diazinon is not considered to be a mutagen. Gene mutation studies involving chromosome aberrations (in vivo and in vitro), and DNA damage (unscheduled DNA synthesis in vitro and in vivo sister chromatid exchange).
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From MSDS
CARCINOGENICITY COMMENTS: Diazinon is not considered to be a carcinogen. NTP chronic feeding studies in rats and mice demonstrated no evidence of oncogenicity.
Rat no observable effect level (NOEL): 40 mg/kg/dy
Mice NOEL: aprox. 30 mg/kg/dy
A search of the EPA's Integrated Risk Information System (IRIS) found no evidence of human carcinogenicity.
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From MSDS
EYES: Flush eyes immediately with fresh water for at least 15 minutes while holding the eyelids open. Remove contact lenses if worn. No additional first aid should be necessary. However, if irritation persists, see a doctor.
SKIN: Remove contaminated clothing. Wash skin thoroughly with soap and water. See a doctor if any signs or symptoms described in this document occur. Discard contaminated non-waterproof shoes and boots. Wash contaminated clothing.
INGESTION: If swallowed, call a physician of Poison Control Center immediately. Drink 1 or 2 glasses of water and induce vomiting by touching the back of throat with a finger. Do not induce vomiting or give anything by mouth to an unconscious or convulsing person.
INHALATION: Move victim to fresh air. If not breathing, give artificial respiration, preferably mouth to mouth. Get medical attention.
NOTES TO PHYSICIAN: This material contains a cholinesterase inhibitor. Measurement of blood cholinesterase activity may be useful in monitoring exposure. If signs of cholinesterase inhibition appear, atropine sulfate is antidotal. 2-PAM (PROTOPAM) is also antidotal and may be used in conjunction with atropine but should not be used alone. This material contains light hydrocarbon liquid and an aspiration hazard may exist.
ADDITIONAL INFORMATION: In case of medical emergencies involving this product, call day or night, (800) 457-2022 OR (800) 454-2333.
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| 2 |
| 1 |
| 0 |
0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe;
N = No information provided by manufacturer; * = Chronic Health Hazard |
| 1997-01-28 |
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Handling/Disposal
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From MSDS
GENERAL PROCEDURES: Keep pesticide in original container. Store in cool dry place, preferably in a locked storage area. Store in an area inaccessible to children and pets. If product freezes, place container in a warm area (68 F or above) not accessible to children or pets and allow to thaw.
STORAGE: During storage, protect from contact with acids.
Bulk storage of this product should be in stainless steel tanks which are fitted with a conservation vent to prevent free exchange between the tank and the atmosphere.
ECOTOXICOLOGICAL INFORMATION: This material is toxic to fish, birds and other wildlife. Birds, especially waterfowl, feeding or drinking on treated areas may be killed. Do not apply directly to water. Do not apply where runoff is likely to occur. This product is highly toxic to bees exposed to direct treatment or residues on plants.
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From MSDS
The Solaris Group is committed to responsible environmental practices and recommends that all of the product be used up, carefully following all label directions and precautions.
If necessary to dispose of partially filled product container, be sure the small product control valve is in the closed position, then securely wrap the container in several layers of newspaper and discard in trash.
EMPTY CONTAINER: Do not reuse container.
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Ingredients from MSDS/Label
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