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Our Science – Smith-Gill Website

Sandra J. Smith-Gill, Ph.D.

Selected Publications
1)  Kourentzi K, Srinivasan M, Smith-Gill SJ, Willson RC.
Conformational flexibility and kinetic complexity in antibody-antigen interactions.
J. Mol. Recognit. 21: 114-21, 2008. [Journal]
2)  Sinha N, Li Y, Lipschultz CA, Smith-Gill SJ.
Understanding antibody-antigen associations by molecular dynamics simulations: detection of important intra- and inter-molecular salt bridges.
Cell Biochem. Biophys. 47: 361-75, 2007. [Journal]
3)  Sinha N, Smith-Gill SJ.
Molecular dynamics simulation of a high-affinity antibody-protein complex: The binding site is a mosaic of locally flexible and preorganized rigid regions.
Cell Biochem Biophys. 43: 253-74, 2005. [Journal]
4)  Li Y, Huang Y, Swaminathan CP, Smith-Gill SJ, Mariuzza RA.
Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces.
Structure (Camb). 13: 297-307, 2005. [Journal]
5)  Li Y, Li H, Yang F, Smith-Gill SJ, Mariuzza RA.
X-ray snapshots of the maturation of an antibody response to a protein antigen.
Nat Struct Biol. 10: 482-488, 2003. [Journal]
6)  Mohan S, Sinha N, Smith-Gill SJ.
Modeling the binding sites of anti-hen egg-white lysozyme antibodies HyHEL-8 and HyHEL-26: An insight into the molecular basis of antibody cross-reactivity and specificity.
Biophys J. 85: 3221-3236, 2003. [Journal]
7)  Lipschultz CA, Yee A, Mohan S, Li Y, Smith-Gill SJ.
Temperature differentially affects encounter and docking thermodynamics of antibody-antigen association.
J Mol. Recognit. 15: 44-52, 2002. [Journal]
8)  Sinha N, Mohan S, Lipschultz CA, Smith-Gill SJ.
Differences in electrostatic properties at antibody-antigen binding sites: Implications for specificity and cross-reactivity.
Biophys J. 83: 2946-68, 2002. [Journal]
9)  Li Y, Lipschultz CA, Mohan S, Smith-Gill SJ.
Mutations of an epitope hot-spot residue alter rate limiting steps of antigen-antibody protein-protein associations.
Biochemistry. 40: 2011–22, 2001. [Journal]

This page was last updated on 8/7/2008.