| Agent Name |
2-Diethylaminoethanol |
|---|
| CAS Number |
100-37-8 |
|---|
| Formula |
C6-H15-N-O |
|---|
| Major Category |
Nitrogen Compounds |
|---|
| Synonyms |
(2-Hydroxyethyl)diethylamine; 2-(Diethylamino)ethanol; 2-(Diethylamino)ethyl alcohol; 2-(N,N-Diethylamino)ethanol; 2-Hydroxytriethylamine; 2-N-Diethylaminoethanol; DEAE; Diaethylaminoaethanol [German]; Diethyl(2-hydroxyethyl)amine; Diethylethanolamine; Diethylmonoethanolamine; Ethanol, 2-(diethylamino)-; N,N-Diethyl-2-aminoethanol; N,N-Diethyl-2-hydroxyethylamine; N,N-Diethyl-N-(beta-hydroxyethyl)amine; N,N-Diethylethanolamine; N,N-Diethylmonoethanolamine; N-Diethylaminoethanol; Pennad 150; beta-Diethylaminoethanol; beta-Diethylaminoethyl alcohol; beta-Hydroxytriethylamine; [ChemIDplus] UN2686 |
|---|
| Category |
Ethanolamines |
|---|
| Description |
Colorless liquid with a nauseating, ammonia-like odor; [NIOSH] |
|---|
| Sources/Uses |
Used as an isocyanate curing agent; [Sullivan, Table 34-2, p. 471] Used as a chemical intermediate for pharmaceuticals, cosmetics, flocculants, emulsifiers, surface coatings, and other organic chemicals (in the chemical, agricultural, plastics, paper, and leather industries); [HSDB] |
|---|
| Comments |
Corrosive to skin; [Quick CPC] Possible cause of asthma; [Reference #1] Causes upper and lower respiratory tract irritation; Rats show signs of upper respiratory irritation with exposures above 120 mg/m3; [NIOSH Criteria Document] May cause allergic contact dermatitis; [CAMEO] Corrosive to the eyes; [ICSC] |
|---|
| Reference Link |
New-onset asthma after exposure to the steam system additive 2-diethylaminoethanol. A descriptive study |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
Yes |
|---|
| TLV (ACGIH) |
2 ppm |
|---|
| PEL (OSHA) |
10 ppm |
|---|
| MAK |
5 ppm |
|---|
| IDLH (NIOSH) |
100 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Human data: A very short exposure (<30 seconds) to a concentration estimated to be less than 100 ppm has resulted in nausea and vomiting within 5 minutes; other persons in the same room also complained of the nauseating odor but did not become ill [Cornish 1965]. |
|---|
| Vapor Pressure |
1.4 mm Hg |
|---|
| Odor Threshold Low |
0.01 ppm |
|---|
| Lethal Concentration |
LCLo (rats) = 4,500 mg/m3/4H |
|---|
| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.011 ppm); Flash point = 49 deg C; VP = 21 mm Hg @ 20 deg C; [HSDB] |
|---|
| Flammability (NFPA) |
2: high ambient temperature required |
|---|
| Adverse Effects |
|---|
| Asthma |
Yes |
|---|
| Skin Sensitizer |
Yes |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIETHYLAMINOETHANOL
|
|---|
