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Introduction | Anatomy | Abstracting, Coding, & Staging | | Hands-on Exercise | | |||||||||
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| Treatment | Surgery (Colon) | Surgery (Rectum) | Radiation Therapy | | Unit Review | | |||||||||||
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Introduction | Anatomy | Abstracting, Coding, & Staging | | Hands-on Exercise | | |||||||||
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| Treatment | Surgery (Colon) | Surgery (Rectum) | Radiation Therapy | | Unit Review | | |||||||||||
Chemotherapy is recommended as adjuvant for Stage III disease (positive lymph nodes)
5-FU alone
5-FU and levamisole (Biological Response Modifier)
5-FU and leucovorin (under clinical evaluation)-ancillary drug
5-FU plus radiation therapy for rectal cancer
Portal vein infusion of 5-FU for known or suspected liver metastases (under clinical evaluation--has shown improvement in palliation but not in survival)
MOF--5-FU, Methyl-CCNU and vincristine (no longer considered to be appropriate adjuvant treatment per NCI because of M-CCNU's renal toxicity and leukemogenic effect)
Not useful for colorectal cancer
Under clinical evaluation
