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January 7, 2009 - New* Gene Abnormality Found to Predict Childhood Leukemia Relapse

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Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

January 7, 2009
The New England Journal of Medicine
NCI’s TARGET Initiative reported the discovery of a novel genetic marker for children with acute lymphoblastic leukemia (ALL) in the January 7, 2009 advance online edition of The New England Journal of Medicine. The genetic alteration identified, IKZF1, should improve clinicians’ ability to identify high-risk patients and better assign these patients to appropriate therapy. [Read More]

Initiative TARGETs Childhood Cancer

November 21, 2006
NCI Cancer Bulletin
Volume 3 / Number 45
Dr. Malcolm Smith, Associate Branch Chief for Pediatrics, Cancer Therapy Evaluation Program, discusses the TARGET Initiative: the reasons behind this pilot project, the primary areas of research focus, and the collaborators involved in establishing TARGET. [Read More]

Cancers Selected for Study
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