Anti-phospho-pkc-delta - Summary: S645,S664,T507,Y313

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Alternate Names
  • Anti-phospho-pkc-delta
Phosphorylation Sites Antibodies
Site Name Alt Res Names Local Sequence MPR Site ID Refs Antibody Name (Cat#) Co. Polyclonal (species) OR Mono. (isotype; clone)
Y313 Y311 PVGIpYQGFE 432 Phospho-PKCdelta (Tyr311) Antibody (2055) Phospho-PKCdelta (Tyr311) Antibody Cell Signaling Technology P (Rabbit)
T507 T505 SRASpTFCGT 295 1, 2, 3, 5, 6, 7 Phospho-PKC (pan) (gamma Thr514) Antibody (9379) Phospho-PKC (pan) (gamma Thr514) Antibody Cell Signaling Technology P (Rabbit)
Phospho-PKC (pan) (zeta Thr410) (190D10) Rabbit mAb (2060) Phospho-PKC (pan) (zeta Thr410) (190D10) Rabbit mAb Cell Signaling Technology M (IgG; 190D10)
Phospho-PKCdelta (Thr505) Antibody (9374) Phospho-PKCdelta (Thr505) Antibody Cell Signaling Technology P (Rabbit)
S645 S643 KARLpSYSDK 305 4, 7 Phospho-PKCdelta (Ser643) Antibody (9376) Phospho-PKCdelta (Ser643) Antibody Cell Signaling Technology P (Rabbit)
PKCd [pS645] (44-966) PKCd [pS645] Invitrogen P (Rabbit)
S664 FAGFpSFVNP 601 Phospho-PKC (pan) (betaII Ser660) Antibody (9371) Phospho-PKC (pan) (betaII Ser660) Antibody Cell Signaling Technology P (Rabbit)
PKCd [pS664] (44-976G) PKCd [pS664] Invitrogen P (Rabbit)

    References

  1. Balendran A, Hare GR, Kieloch A, Williams MR, Alessi DR. 2000. Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. FEBS Lett 484:217-223 (Abstract) [site(s): T507]
  2. Le Good JA, Ziegler WH, Parekh DB, Alessi DR, Cohen P, Parker PJ. 1998. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science 281:2042-2045 (Abstract) [site(s): T507]
  3. Liu Y, Graham C, Li A, Fisher RJ, Shaw S. 2002. Phosphorylation of PKC-theta activation loop and hydrophobic motif regulate its kinase activity but only activation loop phosphorylation is critical to in vivo NFkB induction. Biochem J 361:255-65 (Abstract) [site(s): T507]
  4. Li W, Zhang J, Bottaro DP, Pierce JH. 1997. Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity. J Biol Chem 272:24550-24555 (Abstract) [site(s): S645]
  5. Rybin VO, Sabri A, Short J, Braz JC, Molkentin JD, Steinberg SF. 2003. Cross regulation of nPKC isoform function in cardiomyocytes: Role of PKCepsilon in activation loop phosphorylations and PKCdelta in hydrophobic motif phosphorylations. J Biol Chem : (Abstract) [site(s): T507]
  6. Stempka L, Girod A, Muller HJ, Rincke G, Marks F, Gschwendt M, Bossemeyer D. 1997. Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form. J Biol Chem 272:6805-6811 (Abstract) [site(s): T507]
  7. Stempka L, Schnolzer M, Radke S, Rincke G, Marks F, Gschwendt M. 1999. Requirements of protein kinase C delta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643. J Biol Chem 274:8886-8892 (Abstract) [site(s): T507,S645]