Organism

Chemical Name: (+)-(S)-4,5,6,7-Tetrahydro-8-chloro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5,1-jk][1,4]benzodiazepine-2-(1H)-thione			Synonyms R86183 TIBO deriv. Tivirapine R-86183 8-Chloro-TIBO 8-ClTIBO NSC636661		AIDS# 002738
					Links to ChemID Plus by CAS# 137332-54-8
					Links to PubChem by AIDS# 002738
S-(+)-ISOMER
C16 H20 Cl N3 S		MW: 321.87			Links to PubMed by CAS#
H-bond donors: 1	H-bond acceptors: 5	PHIA (Flexible Bonds): 4.17	Calc. LogP (MDL QSAR): 3.03
Company: JANSSEN			Calc. LogP (KowWin): 4.51
Lines of Data: 50	Lines of Data: 12	Anti-OI data: 0	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 21	Number of References: 5	Number of References: 0	Lipinski: 4 (Score, out of 4)
Classes: NON-NUCLEOSIDE RT INHIBITORS; TIBO ANALOGS; BENZODIAZEPINES