Organism

Chemical Name: Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]			Synonyms Sandimmune Cyclosporine Ciclosporin Ramihyphin A Cyclosporin A Neoplanta Sang-35 CSA CsA NSC290193		AIDS# 000146
					Links to ChemID Plus by CAS# 59865-13-3
					Links to PubChem by AIDS# 000146
ISOLATED FROM TOLYPOCLADIUM INFLATUM
C62 H111 N11 O12		MW: 1202.62			Links to PubMed by CAS#
H-bond donors: 5	H-bond acceptors: 23	PHIA (Flexible Bonds): 33.49	Calc. LogP (MDL QSAR): 0.8
Company: NOVARTIS (SANDOZ)			Calc. LogP (KowWin): 1
Lines of Data: 48	Lines of Data: 16	Lines of Data: 29	TB Min MIC	TB Min IC50	Links to NIST by AIDS#
Number of References: 14	Number of References: 9	Number of References: 13	Lipinski: 2 (Score, out of 4)
Classes: PEPTIDES, CYCLIC; IMMUNOSUPPRESSANTS; CALCINEURIN INHIBITORS; CALCIUM FLUX REGULATORS; NATURAL PRODUCTS; CYCLOSPORINS; HEPATITIS C (HCV) INHIBITORS