Transformative R01 Round Table Discussion: 3-D Tissue Models

Overview

The NIH has issued a Roadmap initiative calling for “Transformative R01” applications (http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-08-029.html). Since this will be a new program, we anticipate that the research community will have many questions. NIH hosted a meeting to help establish a dialog and begin to address some of these questions for one of the “areas of highlighted need that have been identified through an NIH strategic planning process” in this initiative, specifically the generation of complex, 3-dimensional tissue models.

The meeting was a “Round Table Discussion” hosted by Dr. Alan Krensky (Director, NIH Office of Portfolio Analysis and Strategic Initiatives) and included about a dozen discussants with experience in the area of in vitro engineered tissues. The discussion was held on the NIH campus, Building 31/Conference Room 10 on Friday, October 24, 2008, 8:30 AM – 12:30 PM. The broad objective was to illuminate potential transformative research for the field—to distinguish between incremental progress and work that will truly disrupt current paradigms, or create new ones where none exist. This was an open meeting, with additional questions collected via e-mail (3DTM@mail.nih.gov). An archived video of the meeting is available on the NIH VideoCast web site at http://videocast.nih.gov/Summary.asp?File=14725.

Invited Discussants

Linda Griffith (Massachusetts Institute of Technology)
Jonathan Garlick (Tufts University)
Anna-Katerina Hadjantonakis (Sloan-Kettering Institute)
Meenhard Herlyn (Wistar Institute)
Christy Haynes (University of Minnesota)
Michelle LaPlaca (Georgia Institute of Technology)
Milan Mrksich (University of Chicago)
David Mooney (Harvard University)
Cheryl Nickerson (Arizona State University)
Shuichi Takayama (University of Michigan)
Herman Vandenburgh (Brown University)
Gordana Vunjak-Novakovic (Columbia University)

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