Ordering Information
Product Images
WB: Active Akt1 (14-276, Lane 1) and Unactive Akt1 (14-279, Lane 2) was probed with anti-phospho PRK2 (1µg/ml).
Anti-Phospho-PRK2 (pan-PDK1 phosphorylation site)
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M, R | WB | Sheep | Affinity Purified | Polyclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: Q16513 # Exhibits a preference for highly basic protein substrates (By similarity).
SIZE: 984 amino acids; 112035 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
DOMAIN:SwissProt: Q16513 The C1 domain does not bind the diacylglycerol (DAG).
PTM: Autophosphorylated. & Activated by limited proteolysis with trypsin (By similarity).
SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr protein ... see more »
SIZE: 984 amino acids; 112035 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
DOMAIN:SwissProt: Q16513 The C1 domain does not bind the diacylglycerol (DAG).
PTM: Autophosphorylated. & Activated by limited proteolysis with trypsin (By similarity).
SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr protein ... see more »
Entrez Gene Number:
Description:
Anti-Phospho-PRK2 (pan-PDK1 phosphorylation site)
Trade Name:
Upstate (Millipore)
Key Applications:
Western Blotting
Species Reactivity:
- Human
- Mouse
- Rat
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Antibody Sub-Category:
Cell Cycle, DNA Replication & Repair
Descriptive Text:
Specificity:
PDK1 phosphorylation sites in a variety of enzymes
Antibody Category:
Nuclear Function
Molecular Weight:
60kDa
Presentation:
100mM Tris-HCl, pH 7.5, 50mM glycine, 0.05% sodium azide before the addition of glycerol to 30%
Storage Conditions:
1 year at -20°C
Modifications:
Phosphorylation
Purification Method:
Immunoaffinity chromatography
Gene Symbol:
- PKN2
- PRKCL2
- Pak-2
- MGC150606
- PRK2
- PRO2042
- PAK2
- MGC71074
Format:
Affinity Purified
Isotype:
IgG
Immunogen:
peptide corresponding to amino acids 810-823 of human PRK2 (YGDRTS[pT]FCGTPEF)
Quality Assurance:
routinely evaluated by immunoblot on active Akt1/PKBa (14-276), but not in unactivated Akt (14-279)
Sales Restrictions:
This product is not available for sale in the United States.
Antibody Type:
Polyclonal Antibody
Host:
Sheep