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Funded Research
2008 NIH Director’s Pioneer Award Program (DP1)
RFA-RM-08-013 |
| PI Name |
Institution Name |
Title |
| CHEN, JAMES K |
STANFORD UNIVERSITY |
Chemical Embryology: Technologies for Manipulating and Visualizing Development |
| DOLMETSCH, RICARDO E |
STANFORD UNIVERSITY |
Using induced pluripotent stem cells to identify the cellular phenotypes of autis |
| EBERWINE, JAMES H |
UNIVERSITY OF PENNSYLVANIA |
Cellular logic of phenotype |
| EPSTEIN, JOSHUA M |
BROOKINGS INSTITUTION CENTER |
Behavioral Epidemiology: Applications of Agent-Based Modeling to Infectious Diseases |
| HAY, BRUCE A |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
Engineering the genetics of wild mosquito populations to fight infectious disease |
| HOCHSCHILD, ANN |
HARVARD MEDICAL SCHOOL |
A new genetic approach for studying prions and other pathogenic protein aggregate |
| LIEBER, CHARLES M |
HARVARD UNIVERSITY |
Nanowire Nanoelectronic/Cell Assemblies as Hybrid Functional Biomaterials |
| LONDON, BARRY |
UNIVERSITY OF PITTSBURGH |
In-Vivo Electrophysiology Imaging |
| MANIATIS, THOMAS P |
HARVARD UNIVERSITY |
Use of induced pluripotent stem cells to study mechanims of familial and sporadic |
| ODOM, TERI WANG |
NORTHWESTERN UNIVERSITY |
Reconstructing Sub-cellular Structure using Plasmonic Metamaterials |
| PARK, HONGKUN |
HARVARD UNIVERSITY |
Nano- and Microelectronic Tools for Interrogating Neuronal Circuits and Networks |
| REGEV, AVIV |
MASSACHUSETTS INST OF TECHNOLOGY
BROAD INSTITUTE |
The temporal reconfiguration of regulatory networks: From yeast to cancer |
| SAMUEL, ARAVINTHAN D |
HARVARD UNIVERSITY |
Biophysical approaches to complex navigational behaviors in larval Drosophila mel |
| TAVAZOIE, SAEED F |
PRINCETON UNIVERSITY |
Towards a cognitive framework for understanding cellular behavior |
| TING, ALICE Y |
MASSACHUSETTS INST OF TECHNOLOGY |
Enabling the study of endogenous proteins in live cells |
| VAN OUDENAARDEN, ALEXANDER |
MASSACHUSETTS INST OF TECHNOLOGY |
Stochastic gene expression in differentiation and development |
2008 NIH Director’s New Innovator Award Program (DP2)
RFA-RM-08-014 |
| PI Name |
Institution Name |
Title |
| BRYANT, ZEV |
STANFORD UNIVERSITY |
Engineering Molecular Motors |
| BUCKANOVICH, RONALD J |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
Using embryonic stem cells to re-create a human tumor microenvironment to develop |
| CARDOZO, TIMOTHY J |
NEW YORK UNIVERSITY SCHOOL OF MEDICINE |
Chemical Biology Design For Malaria |
| CHRISTMAN, KAREN L |
UNIVERSITY OF CALIFORNIA, SAN DIEGO |
Engineering a Dynamic Extracellular Matrix Microenvironment |
| COBB, BRIAN A |
CASE WESTERN RESERVE UNIVERSITY |
T cell Dependent Immune Responses to Carbohydrate Antigens |
| COHN, RONALD D |
JOHNS HOPKINS UNIVERSITY |
Maintenance of Skeletal Muscle Mass: Lessons Learned from Hibernation |
| DUAN, XIANGFENG |
UNIVERSITY OF CALIFORNIA, LOS ANGELES |
Integrated Free-standing Nanoprobes for Neuroscience and Beyond |
| FIELD, SETH J |
UNIVERSITY OF CALIFORNIA, SAN DIEGO |
Phosphoinositides Provide Unique Insights into Cell Biology and Pathophysiology |
| GITAI, ZEMER |
PRINCETON UNIVERSITY |
Discovering Antibiotic Drugs & Targets via High-Throughput Bacterial Cell Biology |
| GITLER, AARON D |
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE |
Using yeast cells to define mechanisms of human neurodegenerative diseases |
| GRACIAS, DAVID H |
JOHNS HOPKINS UNIVERSITY |
Minimally Invasive Micro-Nanoscale Tools and Devices for Medicine |
| HAYNES, CHRISTY L |
UNIVERSITY OF MINNESOTA |
Immune System-On-A-Chip For Quantitative Analysis Of Cell Interactions During All |
| KESLER, SHELLI R |
STANFORD UNIVERSITY SCHOOL OF MEDICINE |
Assessment and Treatment of Cognitive Deficits in Breast Cancer |
| KIRICHOK, YURIY |
UNIVERSTITY OF CALIFORNIA, SAN FRANCISCO |
Molecular Biophysics of Mitochondrial Membranes: Defining Future Therapeutic Targ |
| KUMAR, SANJAY |
UNIVERSITY OF CALIFORNIA, BERKELEY |
Cellular mechanobiology: Biophysics and therapeutics |
| KUO, CHAY T |
DUKE UNIVERSITY MEDICAL CENTER |
Discovering pathways regulating neurogenesis and brain remodeling after injury |
| MAHAL, LARA K |
UNIVERSITY OF TEXAS AT AUSTIN |
An integrated systems approach to deconstructing glycosylation |
| MURPHY, COLEEN TARA |
PRINCETON UNIVERSITY LEWIS-SIGLER INSTITUTE |
Slowing the Ticking Clock: C. elegans Screens for Reproductive Aging Regulators |
| NOMA, KENICHI |
WISTAR INSTITUTE |
A New Methodology to Decipher Three-Dimensional Genome Structure |
| OHI, MELANIE DIANE |
VANDERBILT UNIVERSITY MEDICAL CENTER |
Multifaceted Approaches for Studying the Structure and Function of Spliceosomes |
| PFENNIG, KARIN S |
UNIVERSITY OF NORTH CAROLINA, CHAPEL HILL |
The origins and maintenance of context-dependent behavior |
| RAMALHO-SANTOS, MIGUEL |
UNIVERSTITY OF CALIFORNIA, SAN FRANCISCO |
Role of pluripotency in development of the germline |
| RECK-PETERSON, SAMARA L |
HARVARD MEDICAL SCHOOL |
Cellular Control of Microtubule-Based Transport: Unraveling its Molecular Mechan |
| SHAPIRO, ERIK |
YALE UNIVERSITY SCHOOL OF MEDICINE |
Single cell MRI of directed cell migration to stroke |
| SHIH, WILLIAM M |
DANA-FARBER CANCER INSTITUTE |
NMR Structure Determination of Membrane Proteins Enabled by DNA Nanotubes |
| WAGERS, AMY JO |
JOSLIN DIABETES CENTER |
Aging and Rejuvenation of the hematopoietic stem cell niche |
| WANG, JUE D |
BAYLOR COLLEGE OF MEDICINE |
The Molecular Interface of Replication Elongation and the Cellular Environment |
| WANG, LEI |
SALK INSTITUTE OF BIOLOGICAL STUDIES |
Genetically Encoding Novel Amino Acids to Investigate Wnt Signaling in C. elegans |
| WU, JOSEPH C |
STANFORD UNIVERSITY SCHOOL OF MEDICINE |
09: Inducing Pluripotency with MiRNAs: New Paradigm Shif in Cell Reprogramming |
| WU, SEAN M |
MASSACHUSETTS GENERAL HOSPITAL |
Generation of functional organs via developmental chimerism |
| ZEITLINGER, JULIA |
STOWERS INSTITUTE FOR MEDICAL RESEARCH |
Investigating Developmental Potential Based on Genome-wide Chromatin Status |
2007 NIH Director's Pioneer Award Program (Re-issuance) (DP1)
RFA-RM-07-005 |
| PI Name |
Institution Name |
Title |
| BARRETT, LISA FELDMAN |
Trustees of Boston College |
Emotions are emergent events constrained by affective and conceptual processes. |
| BEARMAN, PETER |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
Social Determinants of the Autism Epidemic |
| BROWN, EMERY NEAL |
MASSACHUSETTS GENERAL HOSPITAL |
A Systems Neuroscience for the Study of General Anesthesia |
| CLANDININ, THOMAS R |
STANFORD UNIVERSITY |
Dissecting the functional anatomy of the visual system: a new way forward |
| COLLINS, JAMES J |
Trustees of Boston University |
A Network Biology Approach to Antibiotic Action and Bacterial Defense Mechanisms |
| GARDEL, MARGARET LISE |
The University of Chicago |
2007 NIH Director's Pioneer Award Program |
| HENSCH, TAKAO |
Children's Hospital Corporation |
Dissecting Non-coding RNA Function in Critical Period Brain Development and Disorders |
| HORWITZ, MARSHALL S |
University of Washington |
NIH Director's Pioneer Award |
| ISMAGILOV, RUSTEM F |
The University of Chicago |
2007 NIH Director's Pioneer Award Program |
| JENSEN, FRANCES E |
Children's Hospital Corporation |
Understanding the Cognitive Impact of Early Life Epilepsy |
| SCHNITZER, MARK J |
STANFORD UNIVERSITY |
Massively Parallel Brain Imaging |
| TURRIGIANO, GINA G |
Brandeis University |
Probing the Structure of the Synapse Using Superresolution Light Microscopy |
2007 NIH Director's New Innovator Award Program (DP2)
RFA-RM-07-009 |
| PI Name |
Institution Name |
Title |
| Aagaard-Tillery, Kjersti |
BAYLOR COLLEGE OF MEDICINE |
Characterization of the Fetal Primate Epigenome and Metabolome Under In Utero |
| Bailey, Ryan |
UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN |
Personalized Clinical Diagnostics and Beyond: Integrated Ring Resonator Arrays |
| Boyden, Edward |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
Novel Tools and Principles for Precisely Controlling Brain Activity |
| Champagne, Frances |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
Epigenetic Mechanisms Mediating the Inheritance of Reproductive Behavior |
| Davies, Sean |
VANDERBILT UNIVERSITY |
Transformed Probiotic Bacteria for Treatment of Chronic Diseases |
| Fernandez-Funez, Pedro |
UNIVERSITY OF TEXAS MEDICAL BR GALVESTON |
Mechanisms of Prion Misfolding |
| Fortune, Sarah |
HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) |
Variation in M. tuberculosis in response to host selection |
| Garraway, Levi |
DANA-FARBER CANCER INSTITUTE |
Defining Melanoma Therapeutic Avenues by Integrative Functional Genomics |
| Gumbo, Tawanda |
UNIVERSITY OF TEXAS SW MED CTR/DALLAS |
Efflux pump inhibitors to reduce duration of antituberculosis therapy |
| Hacohen, Nir |
MASSACHUSETTS GENERAL HOSPITAL |
Revealing pathogen-sensing pathways using RNAi libraries |
| Heldwein, Ekaterina |
TUFTS UNIVERSITY BOSTON |
Structural and mechanistic studies of herpesvirus entry into host cells |
| Hochedlinger, Konrad |
MASSACHUSETTS GENERAL HOSPITAL |
Reprogramming of somatic cells by defined factors |
| Jacobson, Kristen |
UNIVERSITY OF CHICAGO |
From Neighborhoods to Neurons and Beyond |
| Jankowsky, Joanna |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
Selective neuronal silencing to study cognitive decline in Alzheimer's disease |
| Jasanoff, Alan |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
Genetically-controlled MRI contrast agents for functional brain imaging |
| Johnson, Mark |
BRIGHAM AND WOMEN'S HOSPITAL |
MicroRNA Biogenesis and the Cancer Proteome |
| Llinas, Manuel |
PRINCETON UNIVERSITY |
Novel antimalarial strategies using metabolomic network discovery |
| Papa, Feroz |
UNIVERSITY OF CALIFORNIA SAN FRANCISCO |
New Tools to Measure and Correct Endoplasmic Reticulum Stress in Single Living |
| Pe'Er, Dana |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
Genetic variation and regulatory networks: Mechanisms and complexity |
| Plath, Kathrin |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
CHROMATIN AND EPIGENETIC INHERITANCE |
| Rape, Michael |
UNIVERSITY OF CALIFORNIA BERKELEY |
Ubiquitin-dependent mechanisms of tissue-specific cell cycle control |
| Rosenblatt, Jody |
UNIVERSITY OF UTAH |
Identification of signals that extrude an apoptotic cell from an epithelium |
| Saghatelian, Alan |
HARVARD UNIVERSITY |
Discovery metabolite profiling of the prolyl peptidases |
| Shorter, James |
UNIVERSITY OF PENNSYLVANIA |
Amyloid elimination by Hsp104 and substrate-optimized variants |
| Sipkins, Dorothy |
UNIVERSITY OF CHICAGO |
Stem cell, tumor and bone marrow microenvironment cross-talk in vivo |
| Spiegel, David |
YALE UNIVERSITY |
Small-Molecule Antibody Recruiting Therapeutics for Treating Human Disease |
| Szigethy, Eva |
UNIVERSITY OF PITTSBURGH AT PITTSBURGH |
Understanding and Treating Neuropsychiatric Symptoms of Pediatric Physical Ill |
| Toomre, Derek |
YALE UNIVERSITY |
Novel TIRF microscopy for analyzing trafficking and signaling at the cell co |
| Yang, Jing |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
Epithelial-Mesenchymal Transition in Tumor Metastasis |
| Yanik, Mehmet |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
Development of on-chip ultra high-throughput whole-animal assay technologies |
NIH Director’s Pioneer Awards Program (DP1)
RFA-RM-06-005 |
| PI Name |
Institution Name |
Title |
| BOAHEN, KWABENA |
STANFORD UNIVERSITY |
Neurogrid: Emulating a Million Neurons in the Cortex |
| CHAKRABORTY, ARUP K. |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
Developing the Principles Governing T Lymphocyte-Mediated Autoimmunity Using an Approach at an Intersection of the Physical and Life Sciences |
| GIERASCH, LILA M. |
UNIVERSITY OF MASSACHUSETTS AMHERST |
NIH Director’s Pioneer Award Application |
| HEALD, REBECCA W. |
UNIVERSITY OF CALIFORNIA BERKELEY |
NIH Director’s Pioneer Award Application |
| KIRKEGAARD, KARLA A. |
STANFORD UNIVERSITY |
Dominant Drug Targets in RNA Viruses |
| KODADEK, THOMAS |
UNIVERSITY OF TEXAS SW MED CTR/DALLAS |
Novel Chemistry to Monitor and Manipulate the Immune System |
| LEE, CHENG C. |
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON |
Reversible Suspended Animation of Non-hibernating Mammals |
| NUDLER, EVGENY |
NEW YORK UNIVERSITY SCHOOL OF MEDICINE |
New Approaches to Fight Infection |
| PIELAK, GARY J. |
UNIVERSITY OF NORTH CAROLINA CHAPEL HILL |
In-Cell NMR of Disease-Related Proteins |
| RELMAN, DAVID A. |
STANFORD UNIVERSITY |
NIH Director's Pioneer Award Application |
| SEGAL, ROSALIND A. |
DANA-FARBER CANCER INSTITUTE |
An extended view of self: human indigenous microbial communities in health and disease |
| SHERLEY, JAMES L. |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
Pioneering Human Adult Stem Cell Discovery and Cellular Medicine |
| XIA, YOUNAN |
UNIVERSITY OF WASHINGTON |
Put Nanostructures to Work for Reading and Controlling Cell Behavior |
NIH Director’s Pioneer Awards Program (Re-issuance) (DP1)
NOT-OD-05-021 |
| PI Name |
Institution Name |
Title |
| CHANDLER, VICKI L |
UNIVERSITY OF ARIZONA |
NIH Director’s Pioneer Award |
| CLINE, HOLLIS T |
COLD SPRING HARBOR LABORATORY |
NIH Director’s Pioneer Award |
| COSMIDES, LEDA |
UNIVERSITY OF CALIFORNIA SANTA BARBARA |
NIH Director’s Pioneer Award |
| DE LANGE, TITIA |
ROCKEFELLER UNIVERSITY |
NIH Director’s Pioneer Award |
| DEISSEROTH, KARL A |
STANFORD UNIVERSITY |
NIH Director’s Pioneer Award |
| HARBURY, PEHR A |
STANFORD UNIVERSITY SCHOOL OF MEDICINE |
NIH Director’s Pioneer Award |
| JARVIS, ERICH D |
DUKE UNIVERSITY MEDICAL CENTER |
NIH Director’s Pioneer Award |
| RANDO, THOMAS A |
STANFORD UNIVERSITY SCHOOL OF MEDICINE |
NIH Director’s Pioneer Award |
| SMITH, DEREK J |
UNIVERSITY OF CAMBRIDGE |
NIH Director’s Pioneer Award |
| TONONI, GIULIO |
UNIVERSITY OF WISCONSIN – MADISON MEDICAL SCHOOL |
NIH Director’s Pioneer Award |
| WATERMAN-STORER, CLARE M |
SCRIPPS RESEARCH INSTITUTE |
NIH Director’s Pioneer Award |
| WOLFE, NATHAN |
JOHNS HOPKINS UNIVERSITY |
NIH Director’s Pioneer Award |
| YUAN, JUNYING |
HARVARD MEDICAL SCHOOL |
NIH Director’s Pioneer Award |
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