Centrin, EF-hand protein, 2, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (2.3 pct) in cDNA library dbEST:9493, OT0216.

Highly represented (1.4 pct) in cDNA library dbEST:10790, NT0312.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; lung; kidney; mixed; vascular; pharynx; uncharacterized tissue; mammary gland; muscle; testis; adrenal gland; pituitary gland; ovary; liver; uterus; eye; pancreas; thyroid; spinal cord; esophagus; umbilical cord; bladder; prostate; connective tissue; placenta; bone marrow; thymus; trachea; skin; embryonic tissue; intestine; pineal gland; ear; ascites; nerve; bone; blood; stomach; heart; salivary gland; ganglia; lymph node; larynx

NCBI

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Finding cDNAs

UGID:140681 UniGene Hs.82794 Homo sapiens (human) CETN2

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Centrin, EF-hand protein, 2 (CETN2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_004335.1	caltractin	H. sapiens	100.0	171
NP_062278.2	centrin 2	M. musculus	98.3	171
NP_001080127.1	centrin, EF-hand protein, 2	X. laevis	93.6	171
XP_001922913.1	PREDICTED: centrin, EF-hand protein, 2	D. rerio	90.1	170
XP_001699499.1	centrin	C. reinhardtii	80.1	165
NP_724103.1	CG31802 CG31802-PA	D. melanogaster	67.7	185
NP_014900.1	Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; interacts with Kar1p; Cdc31p	S. cerevisiae	63.5	145
NP_190605.1	ATCEN2 (CENTRIN2); calcium ion binding	A. thaliana	60.2	161
NP_503386.1	T21H3.3	C. elegans	53.1	143
XP_961276.2	calmodulin	N. crassa	52.1	142

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	X
Map position:	Xq28
UniSTS entry:	Chr X	STS-X72964

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BT007256.1	Homo sapiens centrin, EF-hand protein, 2 mRNA, complete cds	P
NM_004344.1	Homo sapiens centrin, EF-hand protein, 2 (CETN2), mRNA	P
CR605856.1	full-length cDNA clone CS0DJ011YN06 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)	P
CR593366.1	full-length cDNA clone CS0DI082YK01 of Placenta Cot 25-normalized of Homo sapiens (human)	P
BC005334.1	Homo sapiens centrin, EF-hand protein, 2, mRNA (cDNA clone MGC:12421 IMAGE:3961448), complete cds	PA
BC013873.2	Homo sapiens centrin, EF-hand protein, 2, mRNA (cDNA clone MGC:10365 IMAGE:3836808), complete cds	PA
AK311940.1	Homo sapiens cDNA, FLJ92207, Homo sapiens centrin, EF-hand protein, 2 (CETN2), mRNA	P
X72964.1	H.sapiens mRNA for caltractin	P

EST sequences (10 of 321) [Show all sequences]

AA987867.1	Clone IMAGE:1592761	kidney	3' read	A
AI074606.1	Clone IMAGE:1673956	mixed	3' read	P
AI089029.1	Clone IMAGE:1670362	brain	3' read
AI091029.1	Clone IMAGE:1689735	mixed	3' read
AI129124.1	Clone IMAGE:1663165	skin	3' read	A
AI130836.1	Clone IMAGE:1709153	heart	3' read	A
BX105552.1	Clone IMAGp998K22667_;_IMAGE:298509	lung		P
AI191010.1	Clone IMAGE:1739245	lung	3' read	A
AI208850.1	Clone IMAGE:1837509	testis	3' read	P
CB158225.1	Clone L18POOL1n1-9-E07	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria