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Finding cDNAs
UGID:695349     UniGene Hs.480190     Homo sapiens (human)   AFF1 Order cDNA clone, Links
AF4/FMR2 family, member 1 (AFF1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_005926.1 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 H. sapiens 100.0 1209
XP_959933.2 hypothetical protein NCU02289 N. crassa 79.0 57
NP_598680.3 myeloid/lymphoid or mixed-lineage leukemia translocated to 2 homolog isoform 2 M. musculus 77.9 1217
XP_001699308.1 ubiquitin conjugating enzyme C. reinhardtii 75.9 58
NP_567791.1 UBC9 (UBIQUITIN CONJUGATING ENZYME 9); ubiquitin-protein ligase A. thaliana 65.7 70

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: placenta; mixed; kidney; brain; uncharacterized tissue; eye; intestine; prostate; ear; liver; mammary gland; blood; thyroid; heart; ovary; pharynx; esophagus; mouth; lung; embryonic tissue; muscle; pancreas; stomach; uterus; spleen; adrenal gland; bone marrow; trachea; epididymis; skin; thymus; pituitary gland; connective tissue; testis; spinal cord; parathyroid; lymph node; bladder; bone; vascular; nerve; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21
UniSTS entry: Chr 4 D4S2815
UniSTS entry: Chr 4 SHGC-59260
UniSTS entry: Chr 4 WI-12383
UniSTS entry: Chr 4 G59617
UniSTS entry: Chr 4 RH36599
UniSTS entry: Chr 4 (n/a)
UniSTS entry: Chr 4 G15939
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

L25050.1 Human serine/proline-rich protein mRNA, complete cds P
NM_005935.2 Homo sapiens AF4/FMR2 family, member 1 (AFF1), mRNA PA
L13773.1 Human AF-4 mRNA, complete cds PA
DQ451148.1 Homo sapiens MLL-AF4 fusion protein (MLL/AF4 fusion) mRNA, partial cds
BC114930.1 Homo sapiens AF4/FMR2 family, member 1, mRNA (cDNA clone MGC:134969 IMAGE:40074243), complete cds P
AK300364.1 Homo sapiens cDNA FLJ61397 complete cds, highly similar to AF4/FMR2 family member 1 P
AK296243.1 Homo sapiens cDNA FLJ55278 complete cds, highly similar to AF4/FMR2 family member 1 P
AK296149.1 Homo sapiens cDNA FLJ55277 complete cds, highly similar to AF4/FMR2 family member 1 P
AK302199.1 Homo sapiens cDNA FLJ61458 complete cds, highly similar to AF4/FMR2 family member 1 PA
AF492831.1 Homo sapiens AF4/MLL fusion protein mRNA, partial cds P
AF177239.1 Homo sapiens cell-line MV4-11 AF4-MLL fusion protein (AF4-MLL) mRNA, partial cds P
AF177238.1 Homo sapiens patient A1 AF4-MLL fusion protein (AF4-MLL) mRNA, partial cds P
AF177237.1 Homo sapiens cell-line MV4-11 MLL/AF4 fusion protein (MLL/AF4) mRNA, partial cds P
AF177236.1 Homo sapiens patient A1 MLL/AF4 fusion protein (MLL/AF4) mRNA, partial cds P
BC017432.1 Homo sapiens AF4/FMR2 family, member 1, mRNA (cDNA clone IMAGE:4720485), partial cds PA
AF024541.1 Homo sapiens MLL-AF4 fusion protein mRNA, partial cds P
L13743.1 Human 5' altered transcript of AF-4 mRNA

EST sequences (10 of 368) [Show all sequences]

AA962321.1 Clone IMAGE:1569913 lung 3' read A
R08887.1 Clone IMAGE:127539 mixed 3' read A
R16488.1 Clone IMAGE:128644 mixed 5' read
R16544.1 Clone IMAGE:129604 mixed 3' read A
R16602.1 Clone IMAGE:129604 mixed 5' read
R16788.1 Clone IMAGE:128644 mixed 3' read A
AI017397.1 Clone IMAGE:1635318 kidney 3' read A
AI041672.1 Clone IMAGE:1667650 parathyroid 3' read A
AI075843.1 Clone IMAGE:1675501 mixed 3' read
AI091838.1 Clone IMAGE:1690961 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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