Protein kinase, DNA-activated, catalytic polypeptide, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (10.0 pct) in cDNA library dbEST:6307, ET0084.

Highly represented (2.1 pct) in cDNA library dbEST:6356, FN0094.

Highly represented (1.1 pct) in cDNA library dbEST:4300, CT0215.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; lung; embryonic tissue; mixed; uncharacterized tissue; liver; intestine; mammary gland; placenta; uterus; eye; stomach; testis; prostate; kidney; pituitary gland; pharynx; bone; lymph; mouth; amniotic fluid; skin; bone marrow; pancreas; spleen; cervix; vascular; larynx; bladder; blood; trachea; connective tissue; muscle; umbilical cord; salivary gland; ear; ascites; heart; ovary; lymph node; thymus; esophagus; nerve; adrenal gland; adipose tissue

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Finding cDNAs

UGID:706841 UniGene Hs.491682 Homo sapiens (human) PRKDC

Links

Protein kinase, DNA-activated, catalytic polypeptide (PRKDC)

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	8
	Map position:	8q11

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_006904.6	Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1, mRNA	P
CR607506.1	full-length cDNA clone CS0DB001YA16 of Neuroblastoma Cot 10-normalized of Homo sapiens (human)
U34994.3	Homo sapiens DNA dependent protein kinase catalytic subunit (PRKDC) mRNA, complete cds; alternatively spliced	P
AB208860.1	Homo sapiens mRNA for protein kinase, DNA-activated, catalytic polypeptide variant protein	P
AK022387.1	Homo sapiens cDNA FLJ12325 fis, clone MAMMA1002125
U35835.1	Human DNA-PK mRNA, partial cds	P
NM_001081640.1	Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 2, mRNA
BC024963.1	Homo sapiens, clone IMAGE:2900772, mRNA	A
AK296833.1	Homo sapiens cDNA FLJ57825 complete cds, highly similar to DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1)	A
BC017494.1	Homo sapiens protein kinase, DNA-activated, catalytic polypeptide, mRNA (cDNA clone IMAGE:3921127), with apparent retained intron	A
U47077.5	Homo sapiens DNA-dependent protein kinase catalytic subunit (DNA-PKcs) mRNA, complete cds	P
BC037968.1	Homo sapiens, Similar to protein kinase, DNA-activated, catalytic polypeptide, clone IMAGE:4508982, mRNA	A

EST sequences (10 of 701) [Show all sequences]

AA992343.1	Clone IMAGE:1613541	uncharacterized tissue	3' read
AA992354.1	Clone IMAGE:1613637	uncharacterized tissue	3' read	A
R17189.1	Clone IMAGE:32026	brain	5' read
AI021892.1	Clone IMAGE:1654646	mixed	3' read
AI022795.1	Clone IMAGE:1654963	mixed	3' read	A
AI049581.1	Clone IMAGE:1700560	kidney	3' read
T06143.1	Clone HFBDP27	brain
AI127415.1	Clone IMAGE:1705904	heart	3' read	A
AI140691.1	Clone IMAGE:1738180	testis	3' read	A
AI141833.1	Clone IMAGE:1691697	heart	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria