Neurofilament, light polypeptide 68kDa, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.2 pct) in cDNA library dbEST:18397, FEBRA1.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; testis; kidney; eye; embryonic tissue; uncharacterized tissue; ear; nerve; ganglia; lung; skin; vascular; connective tissue; esophagus; mixed; prostate; placenta; thymus; spinal cord; uterus; liver; pancreas; thyroid; pineal gland; bone marrow

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Finding cDNAs

UGID:912208 UniGene Hs.521461 Homo sapiens (human) NEFL

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Neurofilament, light polypeptide 68kDa (NEFL)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_858626.1	PREDICTED: similar to neurofilament, light polypeptide isoform 3	C. lupus familiaris	99.2	500

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	8
	Map position:	8p21

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AK127430.1	Homo sapiens cDNA FLJ45522 fis, clone BRTHA2025869, highly similar to Neurofilament triplet L protein	P
NM_006158.2	Homo sapiens neurofilament, light polypeptide 68kDa (NEFL), mRNA	P
BC066952.1	Homo sapiens neurofilament, light polypeptide 68kDa, mRNA (cDNA clone MGC:87388 IMAGE:5264373), complete cds	PA
AK225975.1	Homo sapiens mRNA for Neurofilament triplet L protein variant, clone: FCC112D04	A
AK057731.1	Homo sapiens cDNA FLJ25002 fis, clone CBL00553, highly similar to NEUROFILAMENT TRIPLET L PROTEIN	P
AK314591.1	Homo sapiens cDNA, FLJ95425
AL713644.1	Homo sapiens mRNA; cDNA DKFZp761K0922 (from clone DKFZp761K0922)	PA
AK299095.1	Homo sapiens cDNA FLJ53642 complete cds, highly similar to Neurofilament triplet L protein
AK075003.1	Homo sapiens cDNA FLJ90522 fis, clone NT2RP4000108, highly similar to Neurofilament triplet L protein	P
BC037803.2	Homo sapiens cDNA clone IMAGE:4796752	A
BC039237.1	Homo sapiens neurofilament, light polypeptide 68kDa, mRNA (cDNA clone MGC:32648 IMAGE:4280159), complete cds	PA
AY156690.1	Homo sapiens light molecular weight neurofilament protein (NEFL) mRNA, complete cds	P

EST sequences (10 of 1365) [Show all sequences]

R14230.1	Clone IMAGE:28422	brain	5' read
AA976892.1	Clone IMAGE:1588346	uncharacterized tissue	3' read
R16320.1	Clone IMAGE:30115	brain	5' read
AA993293.1	Clone IMAGE:1623953	embryonic tissue	3' read	A
AI126135.1	Clone IMAGE:1735500	testis	3' read	A
AI129718.1	Clone IMAGE:1712102	uterus	3' read	A
BX098007.1	Clone IMAGp998M18269_;_IMAGE:44648	brain		A
BX099529.1	Clone IMAGp998G115017_;_IMAGE:2038306	brain
AI266718.1	Clone IMAGE:1899711	kidney	3' read	A
AI267589.1	Clone IMAGE:2038306	brain

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria