Down syndrome critical region gene 3 (DSCR3)

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UGID:198123 UniGene Hs.369488 Homo sapiens (human) DSCR3

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Down syndrome critical region gene 3 (DSCR3)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_006043.1	Down syndrome critical region protein 3	H. sapiens	100.0	296
XP_001170081.1	PREDICTED: similar to DCRA isoform 1	P. troglodytes	99.6	248
NP_001084757.1	hypothetical protein LOC431791	X. laevis	86.9	296

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; kidney; lung; intestine; spleen; thymus; testis; placenta; liver; bone marrow; mixed; skin; uterus; bladder; stomach; eye; embryonic tissue; mammary gland; blood; lymph node; mouth; prostate; connective tissue; vascular; trachea; lymph; ear; muscle; ascites; salivary gland; bone; pharynx; heart; pancreas; thyroid; ovary; pituitary gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	21
Map position:	21q22.2
UniSTS entry:	Chr 21	G20460
UniSTS entry:	Chr 21	A005S21
UniSTS entry:	Chr 22	GDB:335751
UniSTS entry:	Chr 21	SHGC-87617	[Map Viewer]
UniSTS entry:	Chr 22	D11S3114
UniSTS entry:	Chr 21	STS-N32500

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BX648191.1	Homo sapiens mRNA; cDNA DKFZp686N0127 (from clone DKFZp686N0127)	A
AK126461.1	Homo sapiens cDNA FLJ44497 fis, clone UTERU3000226	P
NM_006052.1	Homo sapiens Down syndrome critical region gene 3 (DSCR3), mRNA
CR624431.1	full-length cDNA clone CS0DB007YE23 of Neuroblastoma Cot 10-normalized of Homo sapiens (human)
BC110655.1	Homo sapiens Down syndrome critical region gene 3, mRNA (cDNA clone MGC:117385 IMAGE:6157155), complete cds	A
AK307465.1	Homo sapiens cDNA, FLJ97413	P
AK312707.1	Homo sapiens cDNA, FLJ93107, Homo sapiens Down syndrome critical region gene 3 (DSCR3), mRNA	P
AK316460.1	Homo sapiens cDNA, FLJ79359 complete cds, highly similar to Down syndrome critical region protein 3	P
AK303624.1	Homo sapiens cDNA FLJ53689 complete cds, highly similar to Down syndrome critical region protein 3
AK300024.1	Homo sapiens cDNA FLJ53650 complete cds, highly similar to Down syndrome critical region protein 3
AK299662.1	Homo sapiens cDNA FLJ59969 complete cds, highly similar to Down syndrome critical region protein 3	P
D87343.1	Homo sapiens mRNA for DCRA, complete cds	P
AJ001867.1	Homo Sapiens mRNA, partial cDNA sequence from cDNA selection, DCR1-11.0	P

EST sequences (10 of 341) [Show all sequences]

AA991730.1	Clone IMAGE:1612815	uncharacterized tissue	3' read	A
AA911787.1	Clone IMAGE:1519671	uncharacterized tissue	3' read
AI039818.1	Clone IMAGE:1663370	skin	3' read
AI049665.1	Clone IMAGE:1700432	kidney	3' read	A
AI085872.1	Clone IMAGE:1632596	mammary gland	3' read	A
AI142800.1	Clone IMAGE:1687877	mixed	3' read	A
CB048054.1	Clone IMAGE:3270623	prostate	3' read	A
CB048055.1	Clone IMAGE:3270623	prostate	5' read
BX111849.1	Clone IMAGp998M13595_;_IMAGE:270900	skin
AI269171.1	Clone IMAGE:1857501	mixed	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria