Anti-phospho-GSK3α (Ser21)
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, R | WB | Sheep | Purified | Polyclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: P49840 # Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN (By similarity).
SIZE: 483 amino acids; 50981 Da
SUBUNIT: Monomer (By similarity).
SIMILARITY: SwissProt: P49840 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. & Contains 1 protein kinase domain.
SIZE: 483 amino acids; 50981 Da
SUBUNIT: Monomer (By similarity).
SIMILARITY: SwissProt: P49840 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. & Contains 1 protein kinase domain.
Entrez Gene Number:
Entrez Gene Summary
Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM]
Description:
Anti-phospho-GSK3α (Ser21)
Specificity:
phospho-GSK3α (Ser21)
Key Applications:
Western Blotting
Species Reactivity:
- Human
- Rat
Isotype:
IgG
Immunogen:
Peptide corresponding to residues 16-26 of human phospho-GSK3 alpha.
Modifications:
Phosphorylation
Molecular Weight:
51kDa
Presentation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Storage Conditions:
2 years at -20°C
Gene Symbol:
- GSK3A
- DKFZp686D0638
Quality Assurance:
routinely evaluated by immunoblot in RIPA lysates from HEK293 cells stimulated with 200ng/ml of IGF1 for 5 minutes
Antibody Category:
Cell Signaling
Antibody Sub-Category:
PI3K, Akt, & mTOR Signaling
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Descriptive Text:
Trade Name:
Upstate (Millipore)
Purification Method:
protein G purification
Format:
Purified
Antibody Type:
Polyclonal Antibody
Host:
Sheep