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UGID:182304     UniGene Hs.306307     Homo sapiens (human)   ROCK1
Rho-associated, coiled-coil containing protein kinase 1 (ROCK1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001143263.1 PREDICTED: serine/threonine kinase 38 like isoform 3 P. troglodytes 49.2 356
XP_001116801.1 PREDICTED: serine/threonine kinase 38 isoform 1 M. mulatta 48.9 329
NP_849380.1 protein kinase family protein A. thaliana 46.9 369

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; uncharacterized tissue; embryonic tissue; placenta; lung; intestine; mammary gland; muscle; liver; skin; vascular; thymus; bladder; amniotic fluid; larynx; adrenal gland; testis; mixed; lymph node; eye; kidney; pancreas; prostate; trachea; spleen; uterus; connective tissue; bone marrow; mouth; thyroid; blood; bone; pharynx; cervix; ear; nerve; lymph; ascites; ovary; heart; stomach; adipose tissue; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q11.1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC041849.1 Homo sapiens Rho-associated, coiled-coil containing protein kinase 1, mRNA (cDNA clone IMAGE:5269982), complete cds A
NM_005406.2 Homo sapiens Rho-associated, coiled-coil containing protein kinase 1 (ROCK1), mRNA
AB208965.1 Homo sapiens mRNA for Rho-associated, coiled-coil containing protein kinase 1 variant protein P
BC113114.1 Homo sapiens Rho-associated, coiled-coil containing protein kinase 1, mRNA (cDNA clone MGC:131603 IMAGE:7961989), complete cds P
DQ786321.1 Homo sapiens clone HLS_IMAGE_824758 mRNA sequence A
AK057038.1 Homo sapiens cDNA FLJ32476 fis, clone SKNMC2000649, highly similar to Human Rho-associated, coiled-coil containing protein kinase p160ROCK mRNA P
AK307388.1 Homo sapiens cDNA, FLJ97336
U43195.1 Human Rho-associated, coiled-coil containing protein kinase p160ROCK mRNA, complete cds P

EST sequences (10 of 361) [Show all sequences]

R21224.1 Clone IMAGE:130271 placenta 3' read A
CA976194.1 Clone IMAGE:6202620 nerve 5' read
AI093872.1 Clone IMAGE:1688298 mixed 3' read
AI142762.1 Clone IMAGE:1634238 mixed 3' read
CB044525.1 Clone IMAGE:3217812 intestine 3' read A
CB044526.1 Clone IMAGE:3217812 intestine 5' read P
AI146533.1 Clone IMAGE:1703016 brain 3' read
BX101499.1 Clone IMAGp998A054660_;_IMAGE:1901068 kidney
CB145833.1 Clone L16HLK3-11-D09 liver 5' read
CB152469.1 Clone C1SNU17-39-F09 cervix 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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