http://www.ccrnp.ncifcrf.gov/~toms/LeftHanded.DNA.html
2000
version = 1.44 of leftyear2000.html 2004 Aug 30
Our Story So Far:
The story line, if you have not had time to
follow
the
previous 235 or so entries
(!) is my slow realization that earth
is being invaded by left handed DNA people ...
|
-
Lexgen.com
advertisement in
Science (7 January 2000, no 5450, p. 37)
will bring functional left handed DNA genomics
to the internet.
as of 2000 January 8
-
An
advertisement for the journal
MCB
on the back cover of the
Journal of Bacteriology January 2000, volume 182, Number 2,
indicates that a paper on left handed DNA fused to right handed
has been accepted. Has there been interbreeding?
as of 2000 January 11
-
At the web site
http://www.genebrowser.com/
if one clicks on the NTE Vector Core Facility link,
one will get a pdf document that
has two left handed DNA molecules that
the company will routinely make for you.
(Thanks to
Steve Mitchell,
smitchell@urogenesys.com,
for pointing this one out!)
as of 2000 January 17
-
Endogen
advertisement in
Nature (13 January 2000, no 6766, p. xi).
This is a clone of
an
earlier DNA image which has been cultured by the PhotoDisc company.
as of 2000 January 18
-
Mergen Ltd
advertisement in
Nature (13 January 2000, no 6766, p. 142).
This is another clone of
an
earlier DNA image which has been cultured by the PhotoDisc company.
Is it taking off exponentially?
Three of Photodisk's images are now left handed, two are right handed
although they were alerted to this problem by me a year ago.
as of 2000 January 18
-
An
Introduction
to Molecular Epidemiology
of left handed DNA people is now available on the web.
The
Molecular Epidemiology Homepage
promotes this field.
as of 2000 January 26
(Thanks to
Andrew Farkas, af@alumni.princeton.edu
for pointing this one out!)
-
Custom left handed DNA made to order!
Now available from
Life Technologies.
as of 2000 January 28
(Thanks to
Steve Mitchell,
smitchell@urogenesys.com,
for pointing this one out!)
-
Maybe Left Handed DNA Causes AIDS?
Is this the thesis of a speculative article in
ABC
News
by Nicholas Regush.
as of 2000 January 31
(Thanks to
David Lloyd-Jones, icomm5@netcom.ca
for pointing this one out!)
-
The upcoming movie
"Let
there be life - Mission to Mars"
from Touchstone Pictures
has some footage of left handed DNA on Mars.
Have we found the source?
as of 2000 February 12
2000 April 10:
Steve Ward
(sward@UMDNJ.EDU)
saw the movie and points out that
"Every example they used was left handed - both the M&Ms and
the computer generated model."
At one point one person says "That DNA looks human." when viewing
a left handed spiral no more than 10 bases long. DUMB!!!!
WARNING, SPOILER:
Actually,
the Martians seeded earth with right handed DNA, then left
because Mars was dying. This is consistant
with them coming back now to take over. They must have messed up
somehow when they seeded Earth!
Or maybe it was a nifty trick to identify and eliminate native
flora?
-
The Seventh Edition of
An Introduction to Genetic Analysis
by Anthony F. Griffiths, Jeffrey H. Miller, David T. Suzuki, Richard C.
Lewontin, and William M. Gelbart (2000)
cover shows a Drosophila melanogaster
flying along with a left handed spiral of DNA trailing it.
This book will get students ready for left handed genetics.
The Fifth Edition also shows a
mouse on the cover with right-handed DNA going in the right ear and
left-handed DNA coming out the left ear.
as of 2000 February 15
(Thanks to
Irwin Tessman,
itessman@purdue.edu
for pointing this one out!)
-
Left handed DNA is found on the cover of the Winter 1999
Oberlin
Alumni Magazine
and three times (of four) in the article from pages 14 to 18
by Peter Gwynne and illustrations by Curtis Parker.
The article
announces "How [Left Handed] DNA can change your life"
and "The Code of [Left Handed] Life" ...
as of 2000 February 25
-
The 2000 cover of
the
Leinco Technologies
product catalog
has left handed DNA.
as of 2000 February 25
(Thanks to
Steven Ward,
sward@UMDNJ.EDU,
for pointing this one out!)
-
In Nature volume 403 24 February 2000 page iii
Novagen
reports the discovery that
left handed DNA was known in ancient times:
"A New Twist on a Classic"
as of 2000 February 29
-
In the same issue of
Nature (volume 403: 24 February 2000 page 831)
Pierce
shows that both right and left handed DNA can be isolated
by cell lysis
as of 2000 February 29
-
In the February 15, 2000 issue of
Genetic Engineering
(volume 20: No. 4)
is an advertisement on page 8
by
Burdick & Jackson
"which clearly shows how Left Handed DNA is synthesized. The
blueprint shows R -> R+R but the structure shows how the actual reaction
goes R -> R + L. Apparently the leading strand is left handed...I had no
idea!!" says David Rhodes.
as of 2000 March 17
(Thanks to
David G. Rhodes,
rhodes@uconnvm.uconn.edu
for pointing this one out!)
-
In the web site of
Genetic Engineering
is a lovely rotating left handed DNA
as of 2000 March 17
-
In
U.S. News & World Report, March 27, 2000,
page 60 Stephen Rountree shows that there was
a sharp sell-off of stocks for biotechnology companies that handle left
handed DNA.
as of 2000 April 6
-
A
Beckman
Coulter
advertisement in
Science (31 March 2000, no 5462, p. 2447)
reports the discovery that the "far-reaching flexibility" of
left handed DNA helps nucleic acid preparation.
(I have to admit I don't understand this at the molecular level.)
as of 2000 April 6
-
In the March 15, 2000 issue of
Genetic Engineering
(volume 20: No. 6)
is an advertisement on page 79
from
ISIS Pharmaceuticals
showing the
antisense inhibition of left handed DNA
as of 2000 April 7
(Thanks to
David G. Rhodes,
rhodes@uconnvm.uconn.edu
for pointing this one out!)
-
The 2000 April 10 cover of
the
Newsweek
shows a man embedded in a left handed DNA.
They have almost completed the entire
human genome
sequence for a left handed DNA person!
When will they get around to the last
three of us who are right handed?
as of 2000 April 8
(Thanks to
Donna M. Fox,
dfox1@gmu.edu
for pointing this one out!
Her letter to Newsweek
appears in the
2000apr22
edition! [Unfortunately they broke the link.])
as of 2001 May 1:
In addition to Newsweek,
Joseph Hutchins
of
JH Models
granted permission to put the image here
and acknowledged the reversal.
-
Celera,
which claims to have sequenced an entire
left handed DNA human genome,
is now offering positions in sequencing
left handed DNA.
as of 2000 April 25
-
The new book
Genome:
The Autobiography of a Species in 23 Chapters
by Matt Ridley
(Harpercollins; ISBN: 0060194979)
describes in detail genes on the chromosomes
of the left handed DNA people
who are replacing
us old right handed DNA humans.
Surprisingly both species have the same number of chromosomes.
Dr. Gilbert says about this book that
"[i]t's a great book, wish I had it earlier in life so that I
could explain to people what I do for a living."
(Thanks to
William A. Gilbert,
Gilbert@Informagen.com
for pointing this one out!)
as of 2000 April 26
-
The 2000/2001 Apoptosis catalog from
R&D Systems
has a very pretty stained glass DNA. There are 3 copies
of left handed cases and one right handed; all seem
also to have some kind of non-twisted distortion.
(Thanks to
David Rhodes,
rhodes@uconnvm.uconn.edu
for pointing this one out!)
as of 2000 May 1
-
Gene silencing apparently functions by the formation
of left handed double stranded RNA,
according to a recent
Nature
(vol 404, 20 April 2000, page 807).
as of 2000 May 1
-
According to a figure in
Nature
(vol 404, 27 April 2000, page 932)
perhaps 1 out of 3 people in the world now have left handed DNA.
as of 2000 May 4
-
An advertisement by Eppendorf Scientific
in
Science
(vol 288, 12 May 2000, page 946)
shows that one can do PCR on left handed DNA.
as of 2000 May 17
-
An advertisement by Qiagen
in
Science
(vol 288, 12 May 2000, page 958)
shows that one can do RT-PCR on left handed RNA.
as of 2000 May 17
-
The front cover of the New York Times (May 7, 2000)
reports next to a picture of a left handed DNA
that "End in Sight in Genome Race"! This is
very bad news for those few of us left who have
right handed DNA!
as of 2000 May 17
(Thanks to
Andrew Farkas, af@alumni.princeton.edu
for pointing this one out!)
-
"Cellular & Developmental Biology", a new catalogue from
Oxford University Press,
is now available for those who
are interested in the effects of left handed DNA
at the higher levels of organization.
as of 2000 May 17
(Thanks to
David G. Rhodes,
rhodes@uconnvm.uconn.edu
for pointing this one out!)
-
Pharmaceutical Laboratory, an industry magazine
has an advertisement for
left handed DNA
Fisher BioReagents.
as of 2000 May 17
(Thanks to
David G. Rhodes,
rhodes@uconnvm.uconn.edu
for pointing this one out!)
-
The
Discovery Channel has decided to run a quiz about Left Handed DNA.
This is a clone of
an
earlier DNA image which has been cultured by the PhotoDisc company.
See the Endogen
entry earlier this year.
The PhotoDisc version of left handed DNA has an
unparalleled niche and
continues to grow. Will it eventually be
the dominant life form? Are we witnessing
competition between left handed DNA forms now that
there are only a few
(I dare not reveal how many)
right handed DNA organisms
left?
as of 2000 May 30
(Thanks to
Gerard R Lazo, lazo@pw.usda.gov,
for pointing this one out!)
-
Repair of lesions in left handed DNA
is being determined according to
Nature
(vol 405, 25 May 2000, page 416).
as of 2000 June 1
-
Two articles in
Nature
(vol 405, 15 June 2000) report:
- on page 821: that gene function can be understood with left handed DNA.
- on page 824: how the yeast two-hybrid system works with left handed DNA.
as of 2000 June 10
-
In
Nature
"A double-take on nature's helix"
(vol 405, 15 June 2000, page 737) reports a spectacular discovery:
"The striking symmetry of the X-ray crystallograph of DNA prepared
by Rosalind Franklin was one of the last clues that led
Watson and Crick to deduce the
double-helical structure of DNA."
|
Oh my! How could I have missed that?
as of 2000 June 15.
UPDATE:
Colin Porter
(colin@icr.ac.uk,
url)
wrote a letter to
Nature
(406, 234, 2000 July 20)
pointing out
this situation.
Nature replied that they will be more vigilant
in the future and pointed to this web site.
as of 2000 June 23.
(Thanks to
Shu-Kun Lin,
lin@mdpi.org,
editor of
Entropy
for pointing the letter out!)
-
The flyer for the
2000 Current Topics in Gene Expression Systems Meeting
in San Diego, sponsored by
Invitrogen,
shows two left handed DNA molecules with people for the rungs.
as of 2000 June 27
(Thanks to
Ilya Lyakhov,
lyakhovi@ncifcrf.gov,
for pointing this one out!)
-
As reported in
Cell
Volume 101, Number 7, June 23, 2000,
Stratagene
now has a way of shrinking people so small that
you can jam a DNA molecule into a cell by hand.
It works for either right or left handed DNA.
Be sure to wear gloves, goggles not required.
(Note: the image on the web site is too small to see,
but it is clearly left handed in the journal "figure".)
as of 2000 July 10
-
On Tuesday June 27, 2000
The New York Times
announced on their front page
that the entire sequence of a left handed DNA person
has been completed!
Since right handed people are being exterminated there are
no plans for doing their sequence.
However, to molify and coddle those few who are "left", they
reported the next day (Wednesday, June 28, 2000 on page A2)
that this was in error.
as of 2000 July 12
(Thanks to
Jack Tessman, jack@silcon.com,
for pointing this one out!)
-
Wow! We made it to
the cover of Cell!
Volume 101, Number 7, June 23, 2000.
as of 2000 July 12
-
In the 2000 July issue
Scientific American
the major companies involved in Left handed DNA sequencing and
the genomics business are reported
(page 54) and the major players in Left handed bioinformatics
are reported on page 60.
This is big business!
as of 2000 July 11
(Thanks to
Donna M. Fox, DFOX1@wpgate.gmu.edu,
for pointing this one out!)
-
An advertisement flyer by
ICN
presents isolation solutions for left handed DNA.
as of 2000 July 12
-
Creation's Seventh
Day
by Robert F. Service
(Science
July 14, 2000: 208 and 235)
reports on how people are trying to insert unusual
amino acids into protein by altering left handed
tRNAs or left handed DNA. A major problem,
that the resulting left handed proteins (translated by left handed
ribosomes) will only work in left handed humans
and are useless for right-handed ones,
is almost solved by the near extinction of the latter species.
as of 2000 July 23
(Thanks to
Barbara MacGregor, bmacgreg@mpi-bremen.de
for pointing this one out!)
-
Quantum Biotech
produces left handed DNA products as featured
on their main web page,
all of their sub-pages
their
2000-2001 catalogue
cover
and all sections of their catalogue
and alternating pages of their catalogue ...
as of 2000 July 23.
2001 May 23.
The company web site is now at
www.qbiogene.com.
(Thanks to
Shu Ouyang, ouyangs@ncifcrf.gov,
for pointing this one out!)
-
Der Spiegel
(15/2000, page 172)
published an article "MENSCHEN NACH MASS"
literally "HUMANS AFTER MEASURE", I suppose
meaning the "Measure of Man" - left handed DNA man that is,
since behind the da Vinci but young modern human
is a left handed DNA.
as of 2000 July 23
Nigel E. A. Crompton, nigel.crompton@psi.ch points out:
Your
literal translation is of course correct but the actual meaning is not
"measure of man". The phrase "nach Mass" means "as you choose to have or
design something". Perhaps a more appropriate way to translate the
phrase would be "Artificial contructrion of Man".
as of 2000 July 28
-
As reported on page 1871
of Science (9 June 2000, 288: 5472)
Lexicon
is defining gene function for drug discovery in
left handed humans, mice and watches.
as of 2000 July 25
(Thanks to
Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx,
for pointing this one out!)
-
As reported on page 20
of Science (7 July 2000, 289: 5476)
Beckman Coulter
is sequencing left handed DNA, check marks, clocks and chess pieces.
as of 2000 July 25
-
The New York Times
OP-ED Wednesday July 19, 2000,
page A29,
show a person behind the bars of a left handed DNA
running horizontally across the page,
as drawn by Milan Trenc.
Entitled "Genes that Let Illness In", by Jerome Groopman
of Harvard,
the story mentions "the pernicious seeds ...
presumed to be present in the blueprint
of the person's DNA ..."
Those of remaining few of
you with right handed DNA had better join the
underground now, otherwise jail is what is in store for you,
...
or worse?
as of 2000 July 25
(Thanks to
Jack Tessman, jack@silcon.com,
for pointing this one out!)
July to Nov material to be added here
I have yet to catch up on cases reported from 2000 July
through 2000 Nov
-
The cover of the
Cruachem
catalogue (presumably 2000) shows a lovely left handed
DNA rising from a synthesis vat.
as of 2000 July 27
(added 2000 Dec 15)
(Thanks to
Jan A. Witkowski,
witkowsk@cshl.org,
for pointing this one out!)
-
ABC News
reports:
"First Draft of Human Genome Is Complete",
World News Tonight,
Date: 06-26-2000,
Correspondent: Ned Potter.
The entire sequence of a left handed DNA person has been completed!
Frank Deis says:
"If you can't see
it well enough they will actually show you the program over the website.
The ladder rotates over the head of Ned Potter as he talks about the genome."
as of 2000 Aug 1
(added 2000 Dec 15)
(Thanks to
Frank Deis,
deis@rci.rutgers.edu,
for pointing this one out!)
-
ABC News
reports:
"Scientists Complete Drafts of Human Genome",
Nightline,
Date: 06-26-2000,
Correspondent: Robert Krulwich.
as of 2000 Aug 1
(added 2000 Dec 15)
(Thanks to
Frank Deis,
deis@rci.rutgers.edu,
for pointing this one out!)
-
SciQuest
shows a left handed DNA
as of 2000 Aug 10
(added 2000 Dec 15)
(Thanks to
an anonymous correspondent
for pointing this one out!)
-
An advertisement by
Infectio Diagnostic Inc
shows left and right handed DNA. See
the similar report by
GMP Genetics, below.
as of 2000 Aug 11
(added 2000 Dec 15)
-
A
Fisher Scientific
flyer shows a blue backboned left-handed DNA.
as of 2000 Aug 21
(added 2000 Dec 15)
-
As reported in Science (20 Oct 2000, vol 290(5491) p. 444)
Remaking Eden: How Genetic
Engineering and Cloning Will Transform
the American Family
by Lee M. Silver.
In other words,
the gig is nearly up for you if you still have right handed DNA!!
as of 2000 Aug 21
(added 2000 Dec 15)
(Thanks to
W. Steven Ward,
wward@hawaii.edu,
for pointing this one out!)
-
The
UCLA Molecular
Cellular and Developmental Biology
home page
has a pretty left handed DNA.
They will investigate the cause of the image and have it fixed.
as of 2000 Aug 23
(added 2000 Dec 15)
(Thanks to
W. Steven Ward,
wward@hawaii.edu,
for pointing this one out!)
-
The cover of
Genome Research
(volume 10 issue 8, August 24)
indicates that great apes now are found to have 50%
left handed DNA.
as of 2000 Aug 24
(added 2000 Dec 15)
(Thanks to
Lior Pachter,
lpachter@math.berkeley.edu,
for pointing this one out!)
-
The cover of the
Geneka
catalogue 2000 shows a left handed
DNA
(as reported in the 25 August 2000 Science, vol 289, no 5483, p. 1268)
as of 2000 Aug 25
(added 2000 Dec 15)
(Thanks to
Jack Tessman,
jack@silcon.com,
for pointing this one out!)
(Permission would have been granted
except that
they have paid to use the left handed twist exclusively.)
-
A new book
The Triple Helix : Gene, Organism, and Environment
by Richard C. Lewontin
(Harvard Univ. Press; ISBN: 0674001591)
shows conclusively that hippos and rhinoceroses have left handed DNA.
as of 2000 Aug 30
(added 2000 Dec 22)
(Thanks to
David Lloyd-Jones,
icomm5@attcanada.ca,
for pointing this one out!)
-
In a featured
news article in the 14 July 2000 issue (number 5477),
Science
on pages 208 and 235
"Creations Seventh Day",
the images were reversed apparently because of
a problem with tiff file formats.
A correction was reported in
Science 2000 289: 1474.
as of 2000 Aug 31
(added 2000 Dec 27)
(Thanks to
Irwin Tessman,
itessman@purdue.edu,
for pointing this one out!)
-
A
Fisher Scientific
advertisement
shows a left handed DNA, but the boxes they are selling
have right handed helices!
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 405)
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
our new secret agent
Alex Tamzon
for pointing this one out!)
-
A
Transgenomic
advertisement
shows a left handed DNA
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 479)
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
Alex Tamzon
for pointing this one out!)
-
A
Digital Instruments
advertisement
shows that surprisingly their AFM can see left handed DNA!
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 497)
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
Alex Tamzon
for pointing this one out!)
-
Another
Quantum Biotechnologies
advertisement
again shows the left handed DNA
on their cover
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 509).
They did not pull the advertisement since
last July.
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
Alex Tamzon
for pointing this one out!)
-
A
Wiley
advertisement
shows a novel form of DNA that is simultaneously left and
right handed, as the backbone splits and passes through itself
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 585)
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
Alex Tamzon
for pointing this one out!)
-
A
Boekel Scientific
advertisement
shows a left handed DNA
(as reported in the September 2000 BioTechniques, vol 29, no 3, p. 607)
as of 2000 Sep 12
(added 2000 Dec 15)
(Thanks to
Alex Tamzon
for pointing this one out!)
-
Is the fall NIH Research Festival again (!)
pushing left handed DNA?
It is hard to tell, but perhaps ...
as of 2000 Sep 20
(added 2000 Dec 15)
(Thanks to
Scott Young,
scott@codon.nih.gov,
for pointing this one out!)
-
An advertising supplement by
Peter Gwynne
(as reported in the 11 August 2000 Science, vol 289, no 5481, p. 1003)
reports opportunities at the graduate level for
research on left handed DNA.
as of 2000 Sep 27
(added 2000 Dec 15)
(Thanks to
Juan Pablo Martinez-Soriano,
jpms@ira.cinvestav.mx
for pointing this one out!)
-
An advertisement flyer by
Applied Biosystems
shows left handed DNA.
as of 2000 Sep 12
(added 2000 Dec 15)
-
An advertisement
by
Sequenom
in the 6 October 2000 Science (vol 290, no 5489, p. 42)
shows left handed DNA behind a young boy clone.
"The Complete Genomics Solution is Here".
(The home page relies entirely on Flash, so if you don't
have flash you will see nothing!)
as of 2000 Sep 12
(added 2000 Dec 15)
-
The
Public Health Genetics Unit
in Cambridge UK
is not involved in left handed DNA gene therapy
but is monitoring developments.
(This gene therapy
is where a right handed DNA person is converted to left handed
DNA by cloning as in the movie
"The 6th Day";
I do not know how
disposal of your original body is handled.)
as of 2000 Oct 4.
Dr. Alison Stewart plans to correct the icon.
as of 2002 Sep 4:
FLASH NEWS!
After two years of painstaking effort,
Alison Stewart
has succeeded in altering the logo!
"At last I have succeeded in changing our left-handed logo (see
website).
... [They will have]
a revised logo when we ran out of our current batch of letterhead
paper.
It was a very large batch. But hooray! - at last we have joined the
ranks of the helically correct. "
(Thanks to
Juan Pablo Martinez-Soriano,
jpms@ira.cinvestav.mx,
for pointing this one out!)
-
Richard Egel reports
on
a new book by
Hartwell et al.
Genetics from Genes To Genomes:
The cover is OK, at least (in contrast to Griffith's 7th edition, which you
caught already). Inside, all the thick-ribbon illustrations, too, are
right-handed throughout. The simple line drawings, however, if they
actually show a twist, are left-handed at an amazing frequency.
p2:fig.P.1, p.144:chpt.5-vignette; p.159:fig.5.15; p.160:fig.5.16;
p.162:fig.5.17-a; p.168:fig.5.20(some); p.189:fig.B(some); p.242:fig.B;
p.469:fig.13.7; p.477:fig.13.14; p.572:fig.16.13+16.14; p.592:fig.17.2;
p.597:fig.17.12-a; p.609:fig.17.23-a; p.648:fig.18.13-a-b.
Fig.5.20-c, in particular, gives 6 "examples" for pairs of sister
chromatids containing containing DNA molecules of either handedness.
While investigating this case I came across the
image of the cover of the CD ROM
which depicts a nice purple left handed DNA
(shown).
as of 2000 Oct 6
(added 2000 Dec 15).
While not allowing the image to be posted here,
Jean Sims Fornango
of McGraw-Hill Higher Ed pointed out that they had
caught the error and will be correcting it.
(Update 2001 Jan 16: Corrections are in progress
)
Richard Egel,
richard.egel@molbio.ku.dk,
(Thanks to
for pointing this one out!)
-
Enzo Biochem
develops
left handed DNA probes, will diagnose
people with left handed DNA (right handed
people are no longer eligible)
and develops left handed genetic
medicines to combat diseases.
as of 2000 Oct 6
(added 2000 Dec 27)
(Thanks to
Juan Pablo Martinez-Soriano,
jpms@ira.cinvestav.mx,
for pointing this one out!)
-
Researcher in Residence
is a cool program,
run by the
Association for Science Education (UK),
in which (left handed DNA) PhD students work with teachers and pupils
in schools.
as of 2000 Oct 10
(added 2000 Dec 15)
(Thanks to
Dean Madden,
dean@madden.tele2.co.uk,
for pointing this one out!)
2002 Aug 31:
I received a note from Steve Wooding who says:
I was intrigued by your 'Left Handed DNA Hall of Fame' and amused to see
that the Wellcome Trust features by proxy: we are a co-funder of the
Researchers in Residence initiative that features at number 72. However,
things have moved on and the scheme is no longer run by the ASE and is now run
by the Sheffield Hallam Department of Science Education, it also has a new logo.
While I have no problem with you continuing to display the old logo along
with the description, I'd appreciate it if you could put a note that the
organisation running the scheme has changed and include a link to the new
scheme (http://www.researchersinresidence.org), just in case one of
our students is reading your page and is interested in getting involved.
Steve
Dr Steven Wooding - Partnerships Project Manager
The Wellcome Trust - http://www.wellcome.ac.uk
210 Euston Road, London NW1 2BE
Telephone: +44 (0)20 7611 8850
Fax: +44 (0)20 7611 8269
-
Maggie Fox of Reuters
reported
on October 12
that the left handed DNA mouse
genome was almost mapped.
For this great 'nearly' event (we can have as many of
these as we want!),
MSNBC put together a cute moving graphic to demonstrate
how DNA sequencing is "almost" done.
They called it
MappingDNA.
Unfortunately you will need Flash on your computer to see it.
as of 2000 Oct 13
(added 2000 Dec 27)
(Thanks to
David Lloyd-Jones, icomm5@netcom.ca
for pointing this one out!)
The image was captured in 2001.
-
As reported in Science (20 Oct 2000, vol 290 (5491) p. 444)
GMP Genetics, Inc.
has demonstrated that there exist diploids that
have one DNA strand left handed and the other right handed.
Apparently the creatures live!
The image that demonstrates this is in their
PDF Brochure
The same image was reported earlier by
Infectio.
as of 2000 Nov 1
-
Pfizer
is looking for exceptional left handed DNA people
(Science, 13 Oct 2000, vol 290(5490) p. 361).
as of 2000 Nov 1
-
Hiperciencia
has a rotating left handed DNA, but you have
to have Shockwave-Flash to see it.
as of 2000 Nov 1
(Thanks to
Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx,
for pointing this one out!)
-
In
Nature
(02 November 2000, 408: 46)
new details of regulation by left handed DNA are reported,
three separate cases of left-handed images are shown.
as of 2000 Nov 3
(Thanks to
Dieter Naf,
dnaf@informatics.jax.org.
for pointing this one out!)
The image is
reprinted by permission from Nature 408:46 copyright 2000
Macmillan Magazines Ltd.
-
In advertising the book
Genome
the book club
QPB
asked "Are you ready to hold your future
in your hands?"
while showing a woman with a left handed DNA.
Clearly if you have right handed DNA you are
in trouble.
as of 2000 Nov 4
-
Celera
shows a left handed DNA on their main page.
(This is a shockwave display and so may not display,
or will display extremely slowly, on your browser.)
Another case appears
as
background
on their press release page.
as of 2000 Nov 6
(Thanks to
Lior Pachter,
lpachter@math.berkeley.edu
for pointing this one out!)
-
Abola et al.,
Nature Structural Biology
7 (November 2000, Structural Genomics Supplement),
973-977.
There's a left-handed dsDNA in Figure 1.
as of 2000 Nov 6
(Thanks to
Dieter Naf, Ph.D.,
The Jackson Laboratory,
dnaf@informatics.jax.org
for pointing this one out!)
-
The
Chemical & Engineering News
"(July 31, 200) featured on its cover and page 31 a left
handed CPK (!) molecule on an article on Proteomics--From Genes to Proteins.
The error was highlighted by Christopher J. Welch of Merck, Rahway, NJ.
Your website was mentioned."
The correction is Aug 14, 2000 CEN p. 8.
as of 2000 Nov 28
(Thanks to
Yock Chai Toong,
yctoong@tm.net.my
for pointing this one out!)
-
The journal
Chemistry in Britain
"did the same on its front cover, back cover and on
page 46 of the May 2000 issue. The error was pointed out by J.D. Dunitz and
E. Hibronner of Switzerland in a letter to editor on July 2000. It is not
surprising that Dunitz could spot the error for he is a very well known X-ray
crystallographer."
as of 2000 Nov 28
(Thanks to
Yock Chai Toong,
yctoong@tm.net.my
for pointing this one out!)
-
The
American Association of Pharmaceutical Scientists
web site had a left DNA handed banner:
but David Rhodes
told them about it and within 5.5 hours
they had corrected it!
(Thanks to
David G. Rhodes,
d.g.rhodes@uconn.edu,
for pointing this one out!)
as of 2000 Dec 1
-
In addition to the
three left handed DNA images already noted,
surprisingly there are three more cases of
similar left-handed images
on page 37 for a total of 6 images in Nature 408 (2000)!
as of 2000 Dec 1
-
The cover of the
Harvard Bioscience
Solutions for Proteomics and Genomics
Molecular Biology
2000/2001
catalogue
has a main left handed DNA and in the background both
left and right handed DNA.
as of 2000 Dec 11
(Thanks to
David G. Rhodes,
d.g.rhodes@uconn.edu,
for pointing this one out!)
-
The University at Albany, State University
of New York
Genomics Center
apparently is
celebrating the official opening of a Left Handed DNA center
as of 2000 Dec 11
(Thanks to
an anonomyous donor
for pointing this one out!)
-
The left handed
'dna48.gif' that previously appeared last year at the
Lawrence Livermore National Laboratory's Biology and
Biotechnology Research Program web page
and subsequently disappeared,
has reappeared at the
The UCSC Center for Biomolecular Science & Engineering!
(The two files are exactly identical.)
as of 2000 Dec 14
(Thanks to
Ronnie Hunag,
jch@stag.gov.tw,
for pointing this one out!)
-
"New media for the new biology"
announces
GenomeWeb.
The new media are indicated by a left handed DNA in the background
and a left handed spiral over their name.
It is nearly 2001, after all, and it is reported
that 99% of H. sapiens now have left handed DNA.
Note that the manditory deadline for substitution by your reverse
clone is approaching, on January 20 of 2001.
as of 2000 Dec 15.
(Note on 2001 Jan 24: I have learned that they will be fixing
their web site
.)
(Thanks to
William Gilbert,
gilbert@Informagen.com,
for pointing this one out!)
-
Steve Ward reports:
I just returned from Cell Biology where I saw two left handed DNAs at
booths of companies and both of them knew it. One was apologetic and promised
to change it, so I promised her I would not report it. The other company knew
it, and even had a three dimensional space filling model of left handed B-DNA
that was intentional! The problem was that the logo was originally a short,
left handed helix that looked vaguely like DNA, so to have the transformation
from the logo to the 3D model, the 3D model had to be reversed! Their website
(http://www.biosearchtech.com/)
does not have the 3D model, but the left handed logo is there.
Biosearch Technologies
provides chemistries for left handed DNA genomics.
as of 2000 Dec 15
(Thanks to
W. Steven Ward,
wward@hawaii.edu,
for pointing this one out!)
-
The MIT
Technology Review
in an article
Medicine Gets Personal,
by Marc Wortman
(January/February 2001, page 76)
reports a method of detecting left handed SNP DNA.
as of 2000 Dec 17
-
Biotechnology at Rensselaer
covers a number of life sciences
involved with left handed DNA.
as of 2000 Dec 18
(Thanks to
an anonomyous donor
for pointing this one out!)
-
Promega
has a very pretty
free wall chart
that demonstrates how cell signalling is controlled by
left handed DNA.
as of 2000 Dec 20
(Thanks to
Torben Kallesoe,
Torben.Kallesoe@sars.uib.no,
for pointing this one out!)
-
The
Pharmacopeia
Software Newsletter, Winter 2000,
reports that people can now use the
GCG software package
for analysis of
left handed DNA (two images of people with left handed DNA and
computer terminals).
as of 2000 Dec 27
-
An advertisment for
WebMD
(found while constructing
the MSNBC Left handed mouse report)
shows an intriguing left handed DNA running like blood
vessels up a right handed arm.
This is a depiction of the process of clone-converting
(cloneverting) you from left to right handed DNA.
as of 2000 Dec 27
-
In an advertisement for
CNRS
(Nature, 21/28 December 2000, volume 408, no. 6815, Recruitment section, page 3)
a left handed DNA spirals out of a high tech mixture.
as of 2001 Jan 8
-
As noted in Science
(volume 289, page 2369, 29 September 2000)
the cover of the AAAS report
Human Inheritable Genetic Modificiations
shows that left handed DNA is inheritable.
(Right handed DNA is not because we are becomming extinct.)
as of 2001 Jan 8
-
In
BioPharm
(January 2000 page 4)
Honeywell Burdick& Jackson
show how an orange right handed DNA will become
both right and left handed at replication.
as of 2001 March 23
(Thanks to
David G. Rhodes,
rhodes@uconnvm.uconn.edu,
for pointing this one out)
For your first visit to the
Left Handed
Hall of Fame
page I suggest that you follow the story
over all of the years.
After that you can look at each year individually
from the table below.
Note: just because a year has gone by does not mean
we haven't found more examples for that year!
1997 and 1998 were bumper crop years
and 1999 beat them more than 2 fold.
2000 was a record year, thanks to help from
friends around the world
(60 of the 97 cases, 63%!).
2001 exceeded even that record!
2002 was lower - are we making headway?
Schneider Lab.
updated:
2009Jan09.14:32:43