BioMarker Discovery Kit (BMDK)
Brian T. Luke (lukeb@ncifcrf.gov)Contents
- Goal of the Investigation
- Method of Examination
- Fingerprint-based versus Biomarker-based Classifiers
- What is the difference between fingerprint-based and biomarker-based classifiers?
- Common fingerprint-based classifiers
- Why are fingerprint-based classifiers not generalizable?
- Proposed biomarker-based classifier
- Concerns for any dataset or classifier
- Identifying Putative Biomarkers
- Form of a biomarker-based classifier
- Determine a consistent meaning for terms
- Replace "panel of markers" with "battery of tests"
- Replace "personalized medicine" with "State-based diagnosis and treatment"
- Analyzing Spectroscopic Datasets
- Datasets
- References