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| Strain Code: | 01XN6 | ||
| Common Strain Name: | Tgfbr2 flox (FVB) | ||
| Strain Nomenclature: | FVB.129S6-Tgfbr2tm1Hlm | ||
| Strain Description: | This is a conditional allele in which exon 2 of the TGF-beta type II receptor (Tgfbr2) gene was flanked by a LoxP site (Chytil et al., 2002). Homozygous mice are fertile and phenotypically normal. This strain has been used to inactivate the Tgfbr2 gene in various tissues and cell types. | ||
| Mutation Information | |||
| Mutation Type: | Targeted | ||
| Gene Name: | transforming growth factor, beta receptor II | ||
| Gene Symbol: | Tgfbr2 | ||
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| Current Genetic Background: | FVB.129S | ||
| Approx. Generation: | |||
| Organ Site : | Various | ||
| Donating Investigator: | Harold L. Moses | ||
| Reference: | Chytil A, Magnuson MA, Wright CVE, Moses HL. Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis 32, 73-75, 2002. PMID: 11857781. | ||
| PubMED Abstract | |||
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