| P01 | Program Project Grant
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.
Program Announcements
P01 Guidelines
New Scoring Procedures
Supplemental Material
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| R01 | Modular Research Grant Application
The modular research grant procedures will affect the NIH peer review process by enabling reviewers to evaluate proposed project budgets on the basis of a general, expert estimate of the total effort and resources required to conduct the proposed research. Reviewers will recommend changes in a proposed project's budget in $25,000 modules. NIH Institute staff will continue to make all final award decisions.
NCI Modular Grants
NIH Modular Research Grant Applications
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| R01 | Research Project Grant
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his specific interest and competencies.
Program Announcements
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| R03 | Small Research Grants
To provide research support specifically limited in time and amount for studies in categorical program areas. Small grants provide flexibility for initiating studies which are generally for preliminary short-term projects and are non-renewable.
Program Announcements
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| R18 | Research Demonstration and Dissemination Projects
To provide support designed to develop, test, and evaluate health service activities, and to foster the application of existing knowledge for the control of categorical diseases.
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| R21 | Exploratory/Developmental Grants
To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.)
Program Announcements
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| R33 | Exploratory/Developmental Grants Phase II
The R33 award is to provide a second phase for the support for innovative exploratory and development research activities initiated under the R21 awardees are generally eligible to apply for R33 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under R33.
Program Announcements
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| R37 | Method to Extend Research in Time (MERIT) Award
To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.
Program Announcements
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| R41 | Small Business Technology Transfer (STTR) Grants - Phase I
To support cooperative R&D projects between small business concerns and research institutions, limited in time and amount, to establish the technical merit and feasibility of ideas that have potential for commercialization. Awards are made to small business concerns only.
Program Announcements
Advice and Information on SBIR/STTR Programs
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| R42 | Small Business Technology Transfer (STTR) Grants - Phase II
To support in-depth development of cooperative R&D projects between small business concerns and research institutions, limited in time and amount, whose feasibility has been established in Phase I and that have potential for commercialization. Awards are made to small business concerns only.
Program Announcements
NIH Guidelines
Advice and Information on SBIR/STTR Programs
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| R43 | Small Business Innovation Research Grants (SBIR) - Phase I
To support projects, limited in time and amount, to establish the technical merit and feasibility of R&D ideas which may ultimately lead to a commercial product(s) or service(s).
Program Announcements
NIH Guidelines
Advice and Information on SBIR/STTR Programs
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| R44 | Small Business Innovation Research Grants (SBIR) - Phase II
To support in-depth development of R&D ideas whose feasibility has been established in Phase I and which are likely to result in commercial products or services. SBIR Phase II are considered "Fast-Track" and do not require National Council Review.
Program Announcements
NIH Guidelines
Advice and Information on SBIR/STTR Programs
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| R55 | James A. Shannon Director's Award
To provide a limited award to investigators to further develop, test, and refine research techniques; perform secondary analysis of available data sets; test the feasibility of innovative and creative approaches; and conduct other discrete projects that can demonstrate their research capabilities and lend additional weight to their already meritorious applications.
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| U01 |
Research Project--Cooperative Agreements
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his specific interest and competencies.
NCI RFA Listing |
| U19 |
Research Program--Cooperative Agreements
To support a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. A cooperative agreement research program generally involves the organized efforts of large groups, members of which are conducting research projects designed to elucidate the various aspects of a specific objective. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award. The investigators have primary authorities and responsibilities to define research objectives and approaches, and to plan, conduct, analyze, and publish results, interpretations and conclusions of their studies. Each research project is usually under the leadership of an established investigator in an area representing his/her special interest and competencies. Each project supported through this mechanism should contribute to or be directly related to the common theme of the total research effort. The award can provide support for certain basic shared resources, including clinical components, which facilitate the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence. |
| U24 |
Resource-Related Research Projects--Cooperative Agreements
To support research projects contributing to improvement of the capability of resources to serve biomedical research. |
| U54 |
Specialized Center-Cooperative Agreements
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These differ from program project in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes, with funding component staff helping to identify appropriate priority needs.
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