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| Strain Number: | 01XH6 | ||
| Common Strain Name: | HB-PLAP | ||
| Strain Nomenclature: | FVB-Tg(ACTB-ALPP)01Jrst | ||
| Release Category (Required for MTA form): C | |||
| Animal Health Report in PDF Format | |||
| Strain Description: | Transgenic mice exhibit a heat-stable alkaline phosphatase activity (human ALPP) in all tissues. | ||
| Mutation Information | |||
| Mutation Type: | Transgenic | ||
| Gene Name: | |||
| Gene Symbol: | |||
| Transgene Name: | human placental alkaline phosphatase | ||
| Transgene Symbol: | PLAP | ||
| Promoter Name: | human beta actin | ||
| Promoter Symbol: | ACTB | ||
| Current Genetic Background: | FVB/N | ||
| Approx. Generation: | 3 | ||
| Organ Site : | |||
| Cryopreservation Mating Scheme: | FVB/N females x hemizygous males | ||
| Genotyping Information: | Protocol 1: Allele: Tg(ACTB-ALPP)01Jrst Protocol 2: Allele: Tg(ACTB-ALPP)01Jrst | ||
| Donating Investigator: | Dr. James Stringer | ||
| Key Reference: | DePrimo SE, Stambrook PJ, Stringer JR. 1996 Human placental alkaline phosphatase as a histochemical marker of gene expression in transgenic mice. Transgenic Res. 6:459-466. PMID: 8840529 [PubMED Abstract] | ||
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