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| Strain Number: | 01XH5 | ||
| Common Strain Name: | GFAP-TV-A | ||
| Strain Nomenclature: | STOCK Tg(GFAP-TVA)10Ech | ||
| Release Category (Required for MTA form): B,D | |||
| Animal Health Report in PDF Format | |||
| Strain Description: | Transgene expressed in astrocytes. No visible phenotype. | ||
| Mutation Information | |||
| Mutation Type: | Transgenic | ||
| Gene Name: | |||
| Gene Symbol: | |||
| Transgene Name: | Subgroup A avaian leucosis viral receptor | ||
| Transgene Symbol: | tv-a | ||
| Promoter Name: | Glial fibrillary acidic protein | ||
| Promoter Symbol: | GFAP | ||
| Current Genetic Background: | STOCK | ||
| Approx. Generation: | |||
| Organ Site : | |||
| Cryopreservation Mating Scheme: | FVB/N females x homozygous males | ||
| Genotyping Information: | Protocol 1: Allele: Tg(GFAP-tv-a)10Ech | ||
| Donating Investigator: | Dr. Eric Holland | ||
| Key Reference: | Holland, E.C., Hively, W.P., DePhino, R.A., and Varmus, H.E. 1998 A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell cycle arrest pathways to induce glioma-like lesions in mice. Genes and Development 12: 3675-3685. PMID: 9851974 [PubMED Abstract] | ||
| Related References: | Holland, E.C. and Varmus, H.E. 1998 Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice. PNAS 95: 1218-1223. PMID: 9448312 [PubMED Abstract] | ||
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